Professor Daiana Stolz is joined by Dr Lennie Derde, who was involved in the recent study 'Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19', published by the New England Journal of Medicine. The pair discuss the use of tocilizumab in targeting interleukin-6 and assess its role in reducing the risk of invasive mechanical ventilation for critically ill patients.