Abstract

Pregnancy, childbirth and the postpartum period in women are factors that contribute to the appearance and exacerbation of tuberculosis. Accumulation in the blood of human chorionic gonadotropin, estrogen, glucocorticoids, aldosterone leading to disrupting hormonal balance and immunosuppression.Studying the impact of tuberculosis during the pregnancy and perinatal period.28 cases of tuberculosis diagnosed in women during pregnancy in 2010-2020 were analyzed. The gestation terms in the analyzed cases were: in the first quarter they were diagnosed with TB 7 (25%), in the second quarter ? 13 (46,4%), in the third quarter ? 8(28,6%).Among the clinical forms of pulmonary TB diagnosed in pregnant women were: infiltrative pulmonary tuberculosis ? 17(60,8%), Nodular pulmonary TB ? 6(21,4%), TB Pleurisy ? 5(17,8%) cases. ;?New Case?; - 21(75%) and ?Retreatment?; in 7(25%) cases.The treatment for sensitive TB was administered in 19(67,8%) cases and for resistant TB ? 9(32,2%).In all cases, treatment was administered according to individual schemes. Adverse reactions of anti-tuberculous treatment were recorded in 6(21,4%) of patients. Positive results of antituberculosis treatment had 23(82,1%) cases. Pregnancy in women diagnosed with TB ended beneficially ? with the birth of a healthy baby in most cases, only in one (3,6%) case the pregnancy was solved with the death of the child. Premature birth was recorded in 1/3 of cases.Diagnosed TB in pregnant women has a severe course. Infiltrative pulmonary TB predominates. Administration of treatment is imposed by the gestation term. Pregnant women with suspicious signs should be evaluated for a timely diagnosis of TB.