ERS Respiratory Channel

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Abstract

The study aimed to evaluate the control of early and late-onset asthma associated with obesity.

Methods. 553 asthma patients and 95 healthy individuals were examined. Patients were divided into groups depending on the age of asthma onset: Group I - 282 patients with late-onset, Group II - 271 patients with early asthma onset. ACQ-5 questionnaire was used to assess asthma control. Statistical analysis of the obtained results was carried out using the SPSS-17 program.

The results of asthma control depending on the BMI showed that the frequency of night and morning symptoms, the degree of activity limitation, the severity of shortness of breath, and difficulties during breathing are more pronounced in patients with accompanying obesity compared to patients with NBW (p = 0.001). This is also confirmed by the general score, which is significantly higher in asthma patients with obesity (2.07±0.08) compared to patients with NBW (1.3±0.08) and overweight (1.35± 0.08) (p = 0.001). The same analysis considering the age of onset showed that in patients with early-onset asthma, the frequency of morning symptoms (p = 0.001), the degree of activity limitation (p = 0.001), the expressiveness of shortness of breath (p = 0.03), and difficulties during breathing (p = 0.007), more pronounced in patients with obesity compared to patients with NBW. The overall assessment of asthma control is poorer in patients with early-onset and obesity (2.14±0.11) compared to late (1.99±0.10).

Conclusions. A lower level of control was established in asthma patients with obesity. The overall control score is lower in patients with early-onset asthma with obesity compared to late-onset asthma.

Abstract

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