Abstract

COPD and bronchiectasis are emerging as another phenotype, more than another co morbidity,  with more  frequent involvement of cardiovascular events. We performed this study to find out cardiovascular disease pattern differences among COPD patients with and without bronchiectasis to identify and manage accordingly.

This comparative cross sectional study was conducted at Khyber Teaching Hospital among COPD patients presented with dyspnoea. HRCT was done to divide them into 2 groups(Gp). Gp 1 with bronchiectasis and Gp 2 without bronchiectasis. ECG and echocardiographic findings were determined in 2 groups. Those having Chronic liver disease, Kidney disease, Interstitial lung disease, Rheumatic heart disease were excluded.

Total of 140 COPD patients with mean age of  57 + 2 years were recruited. Forty three percent were having bronchiectasis of some degree. Echocardiographic findings showed mean RVSP of more than 60 mmHg in Gp 1 vs 30mmHg in Gp 2. However, diastolic dysfunction is more in Gp2 65 percent. HFpEF vs HFrEF were found in 30 vs 40 percent of the COPD patients. McConell`s sign was seen in 2 patients with bronchiectasis. LV clot was seen in 5 patients. Different types of arrhythmias were seen in almost 60 patients, multi- focal tachycardia being the commonest one.

Conclusion: COPD is associated with Cardiovascular disease in more than 60 percent of patients admitted with acute exacerbation and age more than 55 years , presence of bronchiectasis increase the risk of cardiovascular disease.