ERS Respiratory Channel

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Abstract

Background

Radial Probe Endobronchial Ultrasonography (RP-EBUS) guided transbronchial biopsy with bronchial brushing is an effective method for sampling tissue from peripheral lung lesions combined with Rapid on-site Evaluation (ROSE), the diagnostic yield of these combined methods are heterogeneous.

Objective

To compare the diagnostic yield of peripheral lung lesions or nodules from the ROSE add-on Radial Probe Endobronchial Ultrasonography (RP-EBUS) guided sheath transbronchial biopsy with bronchial brushing versus the RP-EBUS alone without ROSE.

Method

All patients aged> 18 years old diagnosed with peripheral lung lesions size<3cm.who underwent RP-EBUS GS TBLB and bronchial brushing

Result

68 patients were randomized equally to the ROSE and control group.There were no significant differences in baseline characteristics. The diagnostic yield was similar;ROSE was 91.18% and control was 88.24% without statistically significant (P=0.999). There was a reduction in procedure durations and amount of sedatives used in ROSE group with statistically significant. Other significant predictors of the diagnostic outcome included the position of RP-EBUS, presence of bronchus sign, size of lesions, and bronchoscopist.

Conclusion

The diagnostic yields of peripheral lung lesions was similar in both group. However, routine ROSE add on RP-EBUS GS TBLB can be reducing in procedure times and decreased sedative use. We recommended ROSE add on RP-EBUS in selected cases. In the future, more larger and multicenter studies are needed to compare the diagnostic yield.

Abstract

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