Post-tuberculosis lung disease (PTLD) is a condition with multiple clinical presentations that has been described in different parts of the world, evidencing serious clinical, structural, and functional sequelae that negatively impact the quality of life of patients.

It sought to identify trends in reference to PTLD and its manifestations, as well as its relationship with multidrug resistance.

A scoping review was carried out, including articles from 2018 to 2022, with the words post-tuberculosis lung disease and drug-resistant tuberculosis. Initially, 91 articles were found, of which 32 were finally analyzed, according to the criteria designed for the investigation.

PTLD is an overlapping spectrum of disorders affecting large and small airways (bronchiectasis and obstructive lung disease), lung parenchyma, pulmonary vasculature, and pleura; and can be complicated by coinfection and hemoptysis.

It has been described more frequently in high TB burden settings. Several studies have found that the average age is 45 years, 88% are men, 45% reported chronic respiratory symptoms, the association with HIV was 16%. The spirometric alteration was documented in 67% and the changes in the radiograph reached 86% and included fibrosis and cavitations.

Some relationship was found with the use of tobacco or with heating systems that use biomass, which strongly relates this entity to the social, cultural, and environmental factors that surround the patient.

It is considered that PTLD is a clinical entity that is barely being described in the world and that it constitutes an important cause of disability in TB survivors, which is more evident in patients with multidrug resistance.