Home Mechanical Ventilation (HMV) in patients with COPD and stable hypercapnia is postulated as a recommended treatment but with a low level of evidence. The objective of this study is to assess what clinical characteristics and comorbidities are related to HMV failure and the consequences in terms of economical cost.

Observational study of COPD carriers of HMV was performed. We performed a logistic regression using STATA, taking into account comorbidities as dependent variables, and calculating the ODDs Ratio with their confidence intervals (IC). The number of admissions, emergencies and deaths, were obtained through SAP, calculating the associated costs. We included 68 patients, 73% men aged 71 years [55-86 years]. The phenotype was emphysema (60.3%) and the obstruction was 42.3% [15-117%]; the prevalent comorbidity was obstructive sleep apnea. The average pCO2 prior to the start of the HMV was 57 mmHg [38-81] and the average pCO2 after initiation 46 mmHg [36-68]. A significant improvement is objectified (decrease >20% pCO2) after the establishment of HMV. There were 61 admissions, 53 emergency room, 489 consultations and only 2 deaths. The patient with hospital admissions, made a healthcare expenditure of around 9.200 Eur. The expenditure of those who required the least admissions as 126 Eur. Reduction pCO2 compared to the onset of HMV in 51.5% of patients. No comorbidities associated with HMV.