Abstract

Introduction:

Risk factors in the development of Acute Respiratory Distress Syndrome (ARDS) among COVID-19 patients is a subject of interest. The increase in the number of cases requires an efficient allocation of resources along with early identification of those who are more likely to develop ARDS. Early intervention is tantamount to improved survival.

Objectives: 

The aim of the study is to identify the clinicodemographic entities of those oxygen-requiring COVID-19 patients who developed ARDS and those who did not.

Methods: 

The study is a retrospective cohort research design which included COVID-19 positive patients who required oxygen support on admission. They were categorized as those who developed ARDS and those who did not. Demographic profile and clinical characteristics were obtained and compared among the two population. 

Results: 

Among those oxygen-requiring COVID-19 patients, the study showed that those who developed ARDS were in more advanced age, with higher body mass index (BMI) and with comorbidities. They were also more febrile with initial symptom of anorexia. Furthermore, most of them have secondary bacterial infection and azotemia. Leukocytosis, thrombocytopenia, high procalcitonin level, low INR and APTT values were evident in those who developed ARDS. 

Conclusion: 

As soon as COVID-19 patients require oxygen, several characteristics as identified in this study can be considered to identify those who have the propensity to developed ARDS. Survival may increase as early intervention is effectuated to those in vulnerable condition.