Background- Post pulmonary TB lung sequalae is gaining increasing recognition as an important contributor to respiratory morbidity and mortality. We aimed to study the burden of OADs among patients who were fully treated for pulmonary TB visiting outpatient clinics for presence of ongoing respiratory symptoms.

Method ? The study was conducted across 23sites across India who were members of Respiratory Research Network (RRN). Demographic details, symptoms, chest X-ray and pre and post bronchodilator spirometry was performed in fully treated for pulmonary TB patients visiting the outpatient clinics for presence of respiratory symptoms.

Results- 618 post pulmonary TB patients from 23 sites in India participated in this study age: 51.4± 14.4 years, male: 60%. The prevalence of COPD (post bronchodilator FEV1/FVC <0.7) was 54%, asthma (pre bronchodilator FEV1/FVC <0.7, post bronchodilator FEV1/FVC >0.7) was 9%, preserved ratio impaired spirometry (PRISM) (pre &post bronchodilator FEV1/FVC >0.7, FVC <80% predicted) was 26%, and only 11% had normal spirometry. Bronchodilator reversibility (FEV1 ?12% and ?200ml) was found in 37% asthmatics, 19% COPD and 14% in PRISM. 73% of those found to have COPD were never smokers. Quantitative radiological scoring on chest X-ray had little impact on association with presence of COPD.

Conclusion- Obstructive airway disease is a common post pulmonary-TB sequelae in India (54% COPD, and 26% PRISM), which merits more recognition and research.