Introduction:

Morocco still one of the endemic countries for tuberculosis, which is responsible for significant morbidity and mortality. The association between pulmonary tuberculosis and chronic obstructive pulmonary disease is less recognized.

Aims and Objectives:

Identify the severity of COPD exacerbation in patients with or without tuberculosis history.

Methods:

We retrospectively reviewed the data of 92 patients hospitalized for COPD in the pneumology department of HASSAN II Hospital in Agadir from January 2020 to February 2023.

Results:

The mean age was 62.15±8.57years (extremes 43-83 years) with a male predominance (91.3%). 62% still smoke with an average consumption of 38. The Fagerström test revealed that 58.8% of smokers were moderately dependent on nicotine.

Comorbidities were present in 81,5% of cases dominated by: pulmonary tuberculosis 22,8%, pulmonary hypertension 17,4%, cardiopathy 13%, pneumothorax 13,1% and neoplasia 12%. Undernutrition was noted in 35.9% of cases.

COPD was classified as stage E according to GOLD 2023 in 87% of cases. The mMRC scale was at 3 in 65.2% and 4 in 27,2% of cases. The exacerbation was moderate in 82.6% and severe in 17.4% of the cases. The etiologies were dominated by infection in 60.9%, pulmonary embolism in 26.1% and decompensation of a cardiopathy in 13% of cases. the CAT score was ? 10 in 85.9% of cases.

No significant association was found between tuberculosis history and severity of exacerbation (p=0.669), number of exacerbations per year (p=0.347), GOLD classification (p= 0.430), dyspnea stage according to mMRC (p=0.292), chronic respiratory insufficiency (p=0.698) and CAT score (p= 0.161).

Conclusion:

In our study, the history of tuberculosis did not correlate with the severity of COPD exacerbation.