INTRODUCTION: Home mechanical ventilation (HMV) adaptation can be clinically challenging. Previously has been believed that initiation and titration of chronic HMV required a hospital admission but this approach becomes impracticable in resource-limited systems with settings such as home and outpatient emerging as alternatives.

We aim to evaluate the patients? perspectives regarding HMV follow up and ascertain differences between patients that started HMV in the outpatient setting or elsewhere.

METHODS: Cross-sectional study of patients with CRF under HMV for at least 30 days, evaluated in our Outpatient Ventilation Clinic between September 2019 and March 2020. Patients filled in a patient experience questionnaire (built by the research team) and the S3-NIV questionnaire.

RESULTS:  The study included 235 patients, mainly males (54.0%), with a median age of 70.0 [64.0?76.0] years.

The health-related benefits and side effects of HMV, based on patients' experience, are described in the figure 1.

CONCLUSION: Outpatient setting was perceived as a positive experience in HMV follow-up, with significant health reported gains. The overall positive patient perspective is corroborated with the results of the validated S3-NIV questionnaire.