OBJECTIVE: Many connective tissue diseases (CTD) are in close clinical relationship with interstitial lung diseases (ILD). At this point, cooperation between Chest Diseases and Rheumatology Clinics can be achieved through a multidisciplinary approach. METHODS: In this study, patients followed up with the diagnosis of CTD-ILD in Chest Diseases and Rheumatology clinics between January 1, 2020 and January 1, 2023 were retrospectively examined. RESULTS:149 CTD-ILD patients were identified (Figure 1). The most common CTDs were Sjögren's syndrome (SS), rheumatoid arthritis (RA), systemic sclerosis (SSc). The mean disease duration for CTDs was 58 months. According to radiological findings, 86 (57.7%) patients had NSIP, 48 (32.2%) patients had UIP, 9 (6%) patients had LIP, and 6 (4%) patients had organizing pneumonia (OP). The mean disease duration for ILD was 35.5 months. NSIP was more common in SSc and SS groups, with 29 (33.7%) patients. Both UIP and OP were most common in the RA group (45.8% vs. 66.6%). LIP was most prominently observed in the SS group (77.8%) (Figure 2). It was determined that 75 (50%) patients were diagnosed with CTD before ILD, 20 (13.3%) patients were diagnosed with ILD before CTD, and 54 (36%) patients were diagnosed with CTD and ILD at the same time. It was determined that 35 (23.5%) of the patients were referred to the Rheumatology clinic by a pulmonologist. Antifibrotic treatment was initiated in 42 of the patients with the diagnosis of progressive pulmonary fibrosis (PPF). CONCLUSION: Multidisciplinary approach increases the chance of early diagnosis of CTD-ILD.