Despite the fact that Serbia is one of the countries with the highest incidence of lung cancer in the world, there is no recent data published on the most significant patient characteristics for the Northern Serbian Province of Vojvodina.

For the purpose of this retrospective study we collected data from 2010-2022. Data were collected from the Institute for Pulmonary Diseases of Vojvodina Hospital Information System and the Lung Cancer Registry. The objective of the study was to determine the most significant demographic and clinical pathological characteristics of lung cancer patients.

Out of 15072 patients eligible for the study, there were 10413 (69.1%) males and 4659 (30.9%) females. The average age of patients was 64.7 years (±8.4) for males and 63.6 years (±9.0) for females (63,43±9,035). The most often lung cancer type was adenocarcinoma (38.0% males vs 49.5% females; p=0.000), squamous cell carcinoma (36.3% males vs 20.5% females; p=0.000) and small-cell lung cancer (14.7% males vs 17.6% females; p=0.000) Most of the patients were diagnosed in Stage IIIb/IV (67.8% males vs 66.4% females) and in ECOG Performance Status 1 (78.5% males vs 79.0% females). Early stage lung cancer (1A) was more often diagnosed among females (5,3% vs. 3,1%; p=0.000). Smoking history data showed 62.9% of man and 63.3% of woman were smokers. Statistically significant difference was observed in gender between never-smokers (5.2% males vs 18.4% females; p=0.000).

Determining the impact of the most important demographic and tumor characteristics of lung cancer patients? is crucial for conducting prevention, diagnosis and treatment strategies for patients in Northern Serbian Province of Vojvodina.