Background:Lung transplantation is an established therapeutic procedure for end stage lung diseases. Especially in cases of PF-ILD, patients can be referred to the transplant centre late and with significant comorbidities.PH associated with PF-ILD is an index of poor outcome and also is an indication for bilateral transplantation. Prevalence,severity and factors associated with PH among IPF v/s non-IPF is unknown.

Objectives:To determine whether prevalence,severity and factors determining the pulmonary hypertension among IPF and Non-IPF is different.

Methods:We conducted a retrospective observational study.We analysed Right Heart catheterisation studies,demographic data,Pulmonary function tests in a series of patients with diagnosed PF-ILD who underwent successful lung transplantation from 2020 to 2022.

Results:We included 61 patients in the study(20 with IPF &41 with Non-IPF);Prevalence of PH was higher in the Non-IPF group(51.28%v/s48.7%,p-value<0.0001)whereas severity with IPF group(40%v/s 9.8%,p-value=0.005). Patients with 6MWT distance of <90m has severe PH (90m v/s 170m,p-value=0.007) whereas patients with walk distance of >180 meter did not have any PH( 130m v/s 180m, p-value=0.009).

Conclusion:Patients with Non-IPF diagnosis has higher prevalence of PH and IPF patients has more severe PH among PF-ILD. 6MWT is a good indicator of presence and severity of PH.

References: Shorr AF, Wainright JL, Cors CS, et al. Pulmonary hypertension in patients with pulmonary fibrosis awaiting lung transplant. Eur Respir J 2007; 30: 715?721.

Abbreviations:6MWT-Six minute walk test,PH-Pulmonary hypertension,IPF-idiopathic pulmonary fibrosis