Introduction & Objective: There is limited study about pathophysiology of bronchiectasis. Bronchiectasis is still a major health problem in India. So this study aims to understand different spirometry indices and their correlation with HRCT scoring by using a quantitative high-resolution CT protocol in patients with stable bronchiectasis.

Materials and Methods: This was a prospective observational study conducted in Department of Pulmonary Medicine, Burdwan Medical College and Hospital, Burdwan, West Bengal over a period of one and half year. Stable patients diagnosed with bronchiectasis by HRCT Thorax fulfilling selection criteria attending outdoor and indoor facility of the Hospital were taken in the study. 

Results:52 patients included in the study, 32 patients (61.5%) were Female and 20 patients (38.5%) were women. Mean age was 40.2 years (40.2 + 14.5 years). Spirometry showed Mixed pattern (52%) Restrictive (32.7%) and obstructive pattern in 7.7 % cases. HRCT htorax showed 83% cystic and 17% cylindrical bronchiectasis. The severity of bronchiectasis, peribronchial thickening, total HRCT thorax scores were inversely related to indices of airway obstruction. There was a significant relationship between peribronchial thickening and FEV1/FVC (r=0.29; p=0.03) & FVC severity (r=-0.27; p=0.05). A significant relationship was present between extent of bronchiectasis and FVC (r=-0.64; <0.001) & FEV1 scores (r=-0.59; p=<0.001). Total HRCT thorax scores were significantly related to FVC (r=-0.42; p= <0.01) & FEV1 (r=-0.31; p=0.02).

Conclusion: Cystic bronchiectasis & mixed spirometry pattern is most common in indian population.