Summary. Chronic obstructive pulmonary disease (COPD) is an issue the significance of which is on an increase worldwide annually. The long-term course of this pathology, frequent exacerbations, rapid progression and the development of a number of complications in overweight patients (more than 30% of the world?s population) make it possible to confirm the relevance of further study of their aggravating course.

The goal of this study is to evaluate the effect of overweight on the quality of life of COPD patients GOLD III.

Materials and methods: 112 patients with chronic obstructive pulmonary disease (COPD GOLD III) were examined in different phases of pathological process, of which 45 with overweight.

Results .The review showed the development of more evident disorders in patients with overweight at exacerbation phase. Thus, the QOL parameters on the scales of " Activity score " - 63,0±3,00 points, "Impact score"- 58,0±2,50 points, ?Symptoms score?- 75,0±3,80 points,  and total SGRQ score 60,0±2,80 points were decreased in overweight patients as compared to patients with normal body weight, where these scores were "Activity score" ? 56,0±2,40 points, " Impact score " ? 51,0±2,30points, ?Symptoms score?- 65,0±3,40points and the total SGRQ score ? 51,0±2,30 points, (p <0.05) .

Conclusions: the course of COPD GOLD III in overweight patients is accompanied by a decrease in the quality of life parameters as compared with COPD GOLD III patients with normal body weight. These changes should be taken into account while assessing the effectiveness of treatment and developing individual rehabilitation programs.