Introduction : Chronic obstructive pulmonary disease (COPD) is a common respiratory disease associated with high morbidity and mortality.COPD patients more frequently experience poor sleep quality compared to healthy subjects. Our study aimed to assess the poor quality of sleep in patients with COPD and the presence of emphysema on the CT scan.Methods:It was a cross-sectional study conducted in department 1 of pneumology from January 2022 to June 2022. We enrolled patients treated for a confirmed COPD and having a thoracic CT scan which confirmed emphysema. Sleep quality was evaluated by the PSQI questionnaire.Results: Forty-one patients were enrolled. The mean age of the patients was 66,24 years  (43 to 97 years). Chronic respiratory failure was reported in 23 cases. A thoracic CT scan showed centrilobular emphysema in 33 cases (80%), pan lobular emphysema in 5 cases (12%), and paraseptal emphysema in 24 cases (59%). In two cases paraseptal emphysema wasn?t associated with other types of emphysema. A median PSQI score was seven.  We noted that 71% of the population had poor sleep quality defined by a PSQI score superior to 5.The presence of centrilobular emphysema was correlated with shorter sleep duration (p=0.034). The presence of mixed emphysema was correlated with a high global PSQI score indicating poor sleep quality (p=0.021), a limited duration of sleep (p=0,001), and a poor subjective sleep quality (p=0,028). Conclusion:According to our study, emphysema impacts sleep quality in COPD patients. Clinicians should take an additional interest in this phenotype of patients whose quality of life is very impaired.