Background
Since the first wave, the ?Gemelli? Polyclinic supported the Italian National Health Service with a digital health program to monitor at home newly diagnosed COVID-19 patients, or after an early discharge from the COVID units.

Objectives
The aim of the analysis was to evaluate the feasibility and safety of the oxygen saturation telemonitoring in COVID-19 patients.

Methods
In this retrospective cohort study, we enrolled patients with initial or recovering non-severe COVID-19 infection. Oxygen saturation, heart rate and body temperature were monitored via a dedicated Bluetooth? pulse oximeter at least twice a day, for at least 14 consecutive days.

Project safety was expressed as the percentage of adverse events (death, hospitalization) out of the total monitored population, and project feasibility was expressed as adherence to protocol, calculated as number of patients without missing days of telemonitoring per total patients.

Results
Out of 105 monitored patients, hospitalization occurred in 3 cases (7.8%), belonging to the initial COVID group. No deaths nor intensive hospitalizations of study subjects were observed. In the overall study population, 92 subjects (87.6%) were defined as adherent to protocol. Most non-adherent patients (61.5%) had only one missing measurement during monitoring. Protocol adherence seems to be comparable for both groups (ongoing COVID group 89.2%, recovering COVID group 86.8%).

Conclusions
This shows one of the first examples of operational telemonitoring service in our Country, suggesting that telemonitoring could be feasible and safe in patients with COVID-19 and could be helpful in reducing both unnecessary hospitalizations and duration of hospital stay.