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Abstract

Introduction: No previous studies have explored the risk factors for developing frailty in Long COVID syndrome.

Objective: To compare the prevalence of risk factors for frailty between perimenopausal women with Long COVID-19 syndrome, women having successfully recovered from COVID-19, and controls from the community.

Methods: Perimenopausal women with a diagnosis of Long COVID-19, women who had successfully recovered from COVID-19, and healthy women of comparable age were included in this study. To characterize the participants, the presence of perimenopausal symptoms and sociodemographic and anthropometric data were collected. Symptom severity and functional disability were assessed with the COVID-19 Yorkshire Rehabilitation Screening (C19-YRS) and the presence of frailty was evaluated considering the Fried criteria.

Results: A total of 195 women were included in the study, distributed over three groups. The Long COVID-19 group showed a higher prevalence of perimenopausal symptoms and the impact of COVID-19. Statistically significant differences were found between Long COVID-19 and the other two groups for the frailty variables. When studying the associations between frailty variables and COVID-19 symptom impact, significant positive correlations were found.

Conclusion: Perimenopausal women with Long-COVID-19 syndrome present more frailty-related factors and experience a higher range of debilitating ongoing symptoms.

Abstract

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