Background: Recommendations regarding Covid-19 vaccines are not standardized across countries.The aim of the study was to evaluate the acceptability of COVID-19 vaccination by the parents of patients with cystic fibrosis (CF) and primary ciliary dyskinesia (PCD) as well as their concerns and attitudes regarding COVID-19 vaccine.

Methods: Parents were invited to complete a questionnaire evaluating the socio-demographic/general health status of the child, the vaccination status of the child/parents, and adherence to the pandemic protection measures. Completion of the questionnaires was done via a telephone call by the same physicians.

Results: There were 133 patients (CF=94, PCD=39) in the study. There was no difference in the rate of COVID-19 vaccination between patients with PCD(74.4 %) and CF (75.5 %) (p=0.88). The rate of COVID-19 vaccination in patients was higher in those who were not infected with COVID-19 (p=0.04). Parents without a history of COVID-19 infection were more likely to have their children vaccinated with COVID-19 (p=0.03). The parents who got the COVID-19 vaccine were more likely to get their children vaccinated (p<0.001). The rate of getting vaccinated with COVID-19 was higher in patients who were vaccinated with influenza (p=0.02). There was no relation between the severity of the underlying disease and the COVID-19 vaccination; educational and employment status of the parent and the COVID-19 vaccination status, respectively ( p=0.63; p=0.58, p=0.50).

Conclusion: Refusal for COVID-19 vaccination seems not to be a problem in children with CF and PCD in our study population.