Abstract

We investigated the independent effects of dry and productive chronic cough (CC) on disease burden  in a sample of adults aged 45-85 years from the Canadian Longitudinal Study on Aging (CLSA). The CLSA is a prospective study including a random sample recruited between 2011-2015 and followed every 3 years. Chronic cough was identified based on a self-reported daily cough in the last 12 months. A GEE model was used to calculate the ORs of impaired social participation activity (SPA), healthcare resource utilisation (HCRU) or any limitations in activities of daily living (ADLs) or instrumental ADLs (IADLs). Chronic cough and the outcomes were considered at baseline and follow-up 1. ORs were adjusted for age, sex, education, BMI, smoking, language, retirement status, asthma/COPD, other chronic diseases. Of the 30,097 participants, chronic cough data was available for both at baseline and follow-up 1 in 26,666. Productive and dry CC were both associated with less frequent SPA, not participating in SPA due to health problems and limitations in ADL (Table 1). Productive CC was also associated with ED visits, and IADL disability while dry CC was associated with visits to a specialist. There was no impact on visiting a family physician. CC is independently associated with impaired social participation, HCRU and limitation in ADL.