Background: Cough severity and quality of life are commonly assessed among patients with chronic cough (CC), however, their relationship with performance of daily activities is rarely evaluated. This study aims to investigate the relationship between subjective cough measures and the activity impairment score taken from the Work Productivity and Activity Impairment (WPAI) questionnaire in employed and non-employed patients. Methods: A prospective observational single center study of patients referred to secondary care. Patients completed the cough severity visual analogue scale (VAS) and Leicester Cough Questionnaire (LCQ). Their activity impairment was assessed using the WPAI questionnaire. The Pearson correlation coefficient (r) was used to report correlations. Results: 43 patients with CC were recruited (29 females; mean (S.D) age, 56.8±13.8 yrs, cough duration 9.5 yrs). Among employed patients (age=53.5), moderately strong correlations were observed between patient subjective cough outcomes and their activity impairment (Figure 1A-B). Among unemployed or retired patients (age 67.2), there was no significant correlation (Figure 1C-D). Conclusion: The observed relationships suggest that chronic coughing hampers daily activities proportionate to cough severity and quality of life, especially amongst employed patients.