Background-most studies on rehabilitation in ILD patients have been done in fairly homogenous groups of patients in controlled, hospital-based settings. We did an RCT on efficacy of home-based PR in heterogenous ILD group.

Aims and Objectives- to asssess the impact of home based PR program on outcome in ILD patients (irrespective of ILD type and severity)

Method- ILD patients visiting OPD were randomized to guided rehabilitation versus standard care for 12 weeks. Baseline assessment was done for quality of life, anxiety, depression in all patients. Rehabilitation group was given standardized, uniform exercise protocol, which was modified by FITT principle to each patient's capacity. Follow up was weekly by telephone and physically at 3, 6 and 12 weeksto assess tolerance and change protocol. All were given education, psychiatric assessment and support irrespective of randomized group

Outcomes-change in exercise capacity (6-MWD), dyspnea, QOL, depresion and anxiety score

Results- 57 patients (M=27, F=30) were randomized to control (n=27) and intervention (n=30) arms. ILD type was HP(17), NSIP(13), UIP(11), OP(8), Sarcoid(3), others(5). 17 patients dropout from study-  intervention(n=12) and control(n=5). Final analysis included 18 in intervention group and 22 controls. In those two completed 12 wk followup Intervention group had more improvement [change at 12 weeks from baseline in intervention group-control group] in 6MWD (+7.3m), FVC (+80ml) and depression score PHQ9 (-1.0) but control group had more improvement quality of life- KBILD (+2.3) and anxiety domains-GAD7 (-1.6). Though none of changes were statistically significant

Patient with worse FVC, 6MWD and exercise desaturation were more likely to dropout