Abstract

Introduction: Asthma is a disease characterized by chronic inflammation of the airways, with high prevalence and impact on children and adolescents. Poor control of the disease promotes impairment in quality of life and sleep. Poor quality sleep can play a direct role in worsening the disease, as one of the severity markers is nocturnal symptoms, directly linked to circadian control. Objective: to evaluate, in asthmatic children, the correlation between asthma control, quality of life, lung function and inflammation with sleep disorders.Methods: Cross-sectional study in which 40 children, aged between 6 and 12 years, of both genders, were evaluated. Asthma control was assessed using the Asthma Control Questionnaire (ACQ6), sleep was assessed according to the presence or absence of disorders using the Sleep Disorders Scale for Children (SDSC), inflammation by exhaled nitric oxide (FeNO), spirometry and Pediatric Asthma Quality of life Questionnaire (PAQLQ).Results: The results showed a correlation between asthma control and Sleep Disordered Breathing (SDB) (0.29), Excessive Daytime Sleepiness (EDS) (0.47) and with the total PAQLQ score (-0.85). The PAQLQ correlated with SDB (-0.35), EDS (-0.42), FeNO correlated with the total SDSC score (0.34). In the regression analysis, each increase of 1 point in SDSC and 1.5 in ACQ6 is equivalent to an increase of 0.10 in FeNO.Conclusion: The lack of clinical control impacts quality of life, interferes with sleep quality and is related to worsening lung inflammation.