Abstract

Early cancer detection through active screening can have a significant impact on mortality rates. Low-Dose CT scan has traditionally been considered an effective method for the early detection of lung cancer, but its widespread use in patients with COVID-19 has allowed us to look at it much more broadly.

Purpose. To analyze the feasibility of performing a Low-Dose CT scan for the diagnosis of malignant neoplasms by analyzing the frequency of detection of cancer of various locations in patients with COVID-19 pneumonia on CT scan.

Materials and methods. We analyzed the results of Low-Dose CT scan of 6325 patients aged 38.5±11.47 years with suspected COVID-19 pneumonia in 2020, SpO2<90% and no data on cancer in the past.

Results. Simultaneously with signs of viral lung disease, 3017 (47.96%) patients had signs of fibrotic changes characteristic of previously transferred inflammatory lung diseases, 98 patients (1.54%) ? of past tuberculosis. Signs of malignant neoplasms were detected in 112 patients (1.77%), which is 4.5 times higher than the all-Ukrainian statistics (0.39%, p < 0.01) for 2020: 48 patients (42.85%) had primary tumor of the upper abdominal cavity (stomach, pancreas, adrenal glands, kidneys) or a secondary impression of the liver; 29 patients (25.89%) ? lung cancer, 17 patients (15.17%) ? metastatic impression of the vertebrae and 18 (16.07%) ? breast cancer. 

Conclusion. The significantly high frequency of detection of malignant neoplasms of various localizations during the Low-Dose CT scan suggests that the COVID-19 pandemic has increased the understanding of the feasibility of this imaging method as a screening for malignant neoplasms of various organs.