Introduction : COPD is the third leading cause of mortality worldwide, and is often undiagnosed, especially in low- and middle-income nations. CAPTURE (COPD Assessment in Primary Care to Identify Undiagnosed Respiratory Disease and Exacerbation Risk) is a short, five-item screening questionnaire developed to screen patients for symptomatic COPD in primary care. Its accuracy at community screening has not been determined.

Aims and Objectives : To determine the accuracy of CAPTURE in identifying symptomatic subjects with COPD at a health screening.

Methods : Consecutive subjects ?18 years of age with no diagnosed respiratory illness undergoing spirometry as a part of health screening were enrolled. Consenting subjects were requested to complete the CAPTURE questionnaire. COPD was diagnosed based on a fixed FEV1/FVC ratio <0.7, and classified based on the GOLD classification. A score >=2 was considered abnormal for the questionnaire. We aimed to determine the accuracy of CAPTURE questionnaire at identifying undiagnosed clinically significant COPD.

Results: From November 2022-Feb 2023, 1453 individuals were screened. Mean age was 52 years (SD=12) with 60% males. 51(3.51%) were diagnosed to have COPD by spirometry criteria (28,28 and 3 subjects in GOLD stage 1,2 and 3, respectively). The CAPTURE questionnaire had an excellent negative predictive value for COPD (97.8%, CI 96.8,98.6). 16 of the 24 individuals with COPD not screened by the questionnaire had GOLD 1 COPD, suggesting that a majority of those with moderate to severe COPD were screened.

Conclusion: The CAPTURE is an easy-to-use accurate questionnaire which can be deployed in screening individuals in the community for the early detection of COPD.