Introduction: Telemedicine is being applied to COVID-19 care. This technology allows for real-time remote monitoring of vital signs, reducing the risk of transmission while providing high-quality care to both self-quarantined patients with mild symptoms and critical patients in hospital. Aims and Objectives: The study is to investigate the application of telemedicine technology to COVID-19 patients for screening and treatment in both at-home and hospital. Methods: The QOCA remote care system monitors 800 isolating cases with remote care packages and a 4G tablet. Case managers and physicians can provide telemedicine appointments and medication, and innovative methods have been developed to improve usage, including online health education and remote care equipment instructions through QR CORE links, as well as video consultations for patients without smartphones. Results: A satisfaction survey among clinical nursing staff found that most respondents felt the remote care package content was comprehensive, the interface was easy to learn, and would like to continue using the system. A majority also agreed that using the remote care system and package would reduce their burden of clinical care work, and that patients/caregivers could easily learn to use the package. While some respondents had concerns about network and Bluetooth connections, a majority agreed to include the remote device as part of their routine equipment, with an average score of 84.7 points. Conclusions: The integration of telemedicine technology improves the quality of care while reducing the workload and exposure of medical staff to viruses.