This interactive video addresses the need for respiratory professionals to effectively diagnose and manage chronic cough in both high-income and low- and middle-income countries (LMICs). It highlights the importance of understanding diverse causes, such as GERD, asthma, and tuberculosis, and the impact of environmental factors like biomass smoke. The video emphasises practical implementation of efficient patient pathways, incorporating multidisciplinary approaches, and considering the profound impact on patients' quality of life. It also covers new drug therapies, such as neuromodulators and novel antitussive agents, to manage chronic refractory cough. The video includes interactive case-based studies with multiple-choice questions, and feedback to enhance learning and application in real-world settings.