Introduction Non-cystic fibrosis bronchiectasis (NCFB) is a chronic respiratory disease characterised by impaired mucociliary clearance, resulting in mucus buildup, chronic bronchial infection and inflammation. Implementing airway clearance techniques (ACTs) is essential.

Objects To assess the clinical utility and practical application of ACTs in outpatient healthcare.

Methods A prospective, non-randomized study was conducted on 9 patients with NCFB referred to our Institute. The patients were divided into two groups: 6 patients who performed ACTs by ELTGOL or T-PEP twice a week for 6 months (Group A) and 3 patients who did not perform ACTs (Group B). Spirometry values, meters covered in the 6-Minute Walking Test (6MWT), degree of dyspnea (mMRC and Borg scales), life quality (St. George's Respiratory Questionnaire-SGRQ, Leicester Cough Questionairre-LCQ, and CAT) and sputum purulence (Murray Scale) were collected at baseline visit (T0) and at 6-months follow-up visit (T1). The improvement in these tests was evaluated over time.

Results 9 patients, 4 male and 5 female, with an average age of 65±9,55 years, were enrolled. Group A patients showed improvements in the evaluated outcomes over time: dyspnea by mMRC (+0.84 (+72.41%) points, p=0.04), life quality by LCQ (+1.24 (+30.92%) points, p=0.01), and sputum purulence by Murray Scale (+0.67 (+40.36%) grades, p=0.02). In addition, exercise tolerance significantly worsened over time in Group B (6MWT: 386.67±137.78 mt at T0 vs 365±143.33 mt at T1, p=0.039).

Conclusions The study suggests including ACTs in NCFB patient management to improve outcomes, including enhanced exercise tolerance.