Session 3: Using human induced pluripotent stem cells for lung research 

16 November, 2023 | 18:00-19:00 CET

Chair: Dr. Ruth Olmer (Germany)
Speakers: Prof. Killian Hurley (Co. Meath, Ireland)

Topics:

• Differentiation of lung tissue-relevant cell-types from hiPSC
• CRISPR/Cas9 gene editing of hiPSC
• Patient-specific and disease modelling

Educational aim:
The audience will learn the process of differentiating lung (epithelial) cells from hiPSC. The benefits and challenges will be discussed of using these cells in your research and in addition the potential for patient-specific modelling will be discussed.

Educational need:
Direct hiPSC differentiation toward lung cells is increasingly applied in research and forms an excellent tool to develop patient-specific models. In addition, gene editing strategies are applied to these cell cultures to model rare genetic diseases. Differentiation of hiPSCs toward lung can still be time consuming and labour intensive, thereby potentially discouraging researchers to start using them. This webinar could provide an introduction to hiPSC culture for lung research and show how valuable the application of this technology is for patient-relevant research.

Learning outcomes:

Understand the benefits of hiPSC culture for patient-relevant research and baseline knowledge on how to start implementing hiPSC research in their own laboratories. They will be made aware of relevant courses to follow and key investigators that can be contacted for input.