2007 - Metabolic Aspects of the Obstructive Sleep Apnea Syndrome (OSAS)

Insulin resistance is often associated with obstructive sleep apnoea syndrome (OSAS) and could contribute to cardiovascular risk in OSAS. Sleep loss and intermittent hypoxia could contribute to the pathogenesis of the metabolic alterations associated with obesity, a common feature of OSAS. The biology of the adipocyte is being increasingly studied, and it has been found that hypoxia negatively affects adipocyte function.

This Research Seminar aimed at discussing:

  • the effects of hypoxia on glucose metabolism and adipocyte function
  • the role of inflammatory activation in OSAS and obesity
  • the alarming rates of obesity and OSAS in children
  • the harmful effects of the metabolic syndrome in OSAS
  • the effects of OSAS treatment on metabolic variables
  • the relationship between daytime sleepiness and hormonal and inflammatory responses.

Speaker(s): F. Giorgino (Bari, Italy)

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