TP230 - PolyI:C and doxorubicin induce a senescent phenotype in basal cells, resulting in impaired lung organoids - LSC 2023 - Post-viral lung diseases - from basic immunology to clinical phenotypes and therapy

Poster Session 2

Chair(s): Peter Openshaw, Hermelijn H. Smits, Philip Hansbro, Antoine-Emmanuel Saliba, Kaylee Worlock, Deepesh Dhakad, Dermot Linden

Session type: Thematic Poster

TP230 - PolyI:C and doxorubicin induce a senescent phenotype in basal cells, resulting in impaired lung organoids

Michelle Brand

EVENTS HOME

Poster
Abstract

Previous presentation

Next presentation

Session content

TP201 Impact of GM-CSF on lung epithelial cell injury and repair in severe influenza virus pneumonia

Theresa Schafer

Poster

Abstract

TP234 Human induced pluripotent stem cell (hiPSC) derived lung organoids for disease modelling

Anna-lena Ament

Poster

Abstract

TP226 Interferon lambda activates the immunoproteasome thereby potentially regulating anti-viral immunity in the lung

Alexandra Sailer

Poster

Abstract

TP227 Eosinophil subtypes affect airway smooth muscle cells migration and ECM-related proliferation in asthma

Airidas Rimkunas

Poster

Abstract

TP228 Residual lung abnormalities following non-hospitalised COVID-19 infection

David Smith

Poster

Abstract

TP229 Respiratory gammaherpesvirus infection exacerbates experimental model of inflammatory bowel disease

Alexis Balthazar

Poster

Abstract

TP230 PolyI:C and doxorubicin induce a senescent phenotype in basal cells, resulting in impaired lung organoids

Michelle Brand

Poster

Abstract

TP232 Cytosolic DNA stress activates the immunoproteasome and primes adaptive T-cell immunity

Laylan Bramasole

Poster

Abstract

TP233 Primary human-derived airway organoid and immune cell co-cultures to facilitate viral infection and drug screening assays

Georgios Stroulios

Poster

Abstract

TP235 Histamine and IL-4 alter airway basal cell differentiation and mobility after injury

Emma Ruysseveldt

Poster

Abstract

TP224 Direct OM-85 airway administration: a new route to prevent viral infections and reduce associated inflammatory sequelae

Christian Pasquali

Poster

Abstract

TP237 Thioredoxin-1 and soluble interleukin-5 receptor subunit alpha as biomarkers of allergic and non-allergic asthma

Jolita Palacionyte

Poster

Abstract

TP238 Lack of IL-33 induction in transcriptional response of primary bronchial epithelial cells in asthma patients

Akshaya Keerthi Saikumar Jayalatha

Poster

Abstract

TP239 Clinical significance of macrophage-lymphocyte rosettes(MLRos) formation in patients with bronchial asthma(BA)

Tamar Saralidze

Poster

Abstract

TP240 Preventive intranasal flagellin protects against a multidrug resistant strain of P. aeruginosa by restoring the effect of gentamicin

Ana Raquel Conduto Dias Maia

Poster

Abstract

TP241 Effect of hybrid rehabilitation on exercise tolerance and peripheral muscle strength in patients with long COVID-19 syndrome

Angelos Vontetsianos

Poster

Abstract

TP242 Involvement of the CXCL12/CXCR4 axis in skeletal muscle wasting in a murine model of early Chronic Obstructive Pulmonary Disease (COPD)

Pauline Henrot

Poster

Abstract

TP243 Kinetics of immune subsets in COVID-19 patients treated with corticosteroids

Apostolos Pappas

Poster

Abstract

TP225 Single-cell transcriptomic analysis reveals an altered bronchial epithelial cell differentiation in asthma

Aurore Gay

Poster

Abstract

TP223 UPF1 is a novel factor in rhinovirus pathogenesis that is deficient in patients with severe asthma

Rocio Teresa Martinez-nunez

Poster

Abstract

TP202 Resolution of inflammation in long COVID

Sean Knight

Poster

Abstract

TP210 COVID-19 pneumonia hospitalizations in different phases of the pandemic in the United States: patient characteristics and clinical outcomes

Stijn Hollemeersch

Poster

Abstract

TP203 Pulmonary impaired COVID-19 patients show pro-fibrotic serum biomarkers after 4 months

Carlos Esteban Machahua Huamani

Poster

Abstract

TP204 Co-cultured, human alveolar organoids recapitulate epithelial-mesenchymal crosstalk in fibrotic lung disease

Carola Voss

Poster

Abstract

TP205 Cellular senescence in severe COPD bronchial epithelium impairs responses to human rhinovirus infection

Hong Guo-parke

Poster

Abstract

TP206 Cigarette smoke delays murine innate immune response against X31 influenza infection

Jelmer Vlasma

Poster

Abstract

TP207 Cigarette smoke induced transient and persistent proteome changes

Marie Zoller

Poster

Abstract

TP208 A circular RNA regulates ion conductance in cystic fibrosis bronchial epithelium

Chiara De Santi

Poster

Abstract

TP209 COVA: results of a double-blind, placebo-controlled phase 2/3 study to assess efficacy and safety of BIO101 in hospitalized COVID-19 patients

Suzana Lobo

Poster

Abstract

TP211 Tnfsf14-driven apoptosis of alveolar macrophages upon influenza infection enables the establishment of secondary pneumococcal pneumonia

Christina Malainou

Poster

Abstract

TP222 Viral pneumonia elicits a lung epithelial repair program in transdifferentiating alveolar macrophages characterized by Plet1

Learta Pervizaj-oruqaj

Poster

Abstract

TP212 Lung stromal cell dynamics are altered by infection experience and ongoing antigen presentation following influenza re-challenge

Julie Worrell

Poster

Abstract

TP213 First study results of the P4O2 long COVID cohort

Nadia Baalbaki

Poster

Abstract

TP214 Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment

Nincy Debeuf

Poster

Abstract

TP216 Pulmonary function 3-6 months following COVID-19: the P4O2 COVID-19 study

Merel E.b. Cornelissen

Poster

Abstract

TP217 Delineating the immune response of lung alveolar macrophages, CD4+ and CD8+ T-cells to viral PAMPs using live microscopy

Shaalan Yasmin

Poster

Abstract

TP218 Impact of the SARS-CoV-2 pandemic on benralizumab-treated patients with severe eosinophilic asthma

Nimrod Laszlo

Poster

Abstract

TP220 Defining the role of SARS-CoV-2 ?v?6 integrin binding in the pathogenesis of COVID-19 induced lung damage

Federica Monduzzi

Poster

Abstract

TP221 Association between cytomegalovirus seropositivity and severity of pulmonary fibrosis

Ana Serezani

Poster

Abstract

TP244 Outcome in total lung capacity associated with oropharyngeal microbiota relative to COVID-19-related ARDS status

Sabine Stadler

Poster

Abstract

CDN Connection Issue

Lung Science Conference 2023

#{title}