Pathogenic variants of genes associated with pulmonary arterial hypertension (PAH): Insights from Trans-Omics for Precision Medicine (TOPMed) study participants - Vienna 2024

Novel aspects in pulmonary hypertension pathobiology

Chair(s): Christina A. Eichstaedt, Andrea Olschewski

Session type: Poster session

Pathogenic variants of genes associated with pulmonary arterial hypertension (PAH): Insights from Trans-Omics for Precision Medicine (TOPMed) study participants

Vasile Foris

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IL-6 regulates GATA6 gene promoter methylation by activating the JAK2/STAT3 signaling pathway to promote PASMCs proliferation

Weijia Liu

Poster

Abstract

Plexiform lesions in human explant lungs with end-stage pulmonary arterial hypertension: µCT analysis

Gitte Aerts

Poster

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Exploring P300/CBP as therapeutic targets for pulmonary arterial hypertension and right ventricular failure

Alice Bourgeois

Poster

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Narciclasine as a Novel Therapeutic Target for Pulmonary Arterial Hypertension: Addressing Glycosylation in Disease Pathophysiology.

Fran?ois Potus

Abstract

Increased DNA Methylation: A Potential Therapeutic Target in Pulmonary Arterial Hypertension

Reem El Kabout

Abstract

LncRNA MIR210HG promotes phenotype switching of pulmonary arterial smooth muscle cells through autophagy-dependent ferroptosis pathway

Ran Wang

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Pulmonary hypertension in patients carrying FLNA loss-of-function variants

Laura Stourm

Poster

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Unlocking the Potential of Genetic Research in Pulmonary Arterial Hypertension: Insights from Clinicians, Researchers and Study Team

Emilia Maria ?wietlik

Poster

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Understanding what drives Genetic Study Participation: Perspectives of Patients, Carers, and Relatives

Emilia Maria ?wietlik

Poster

Abstract

Pathogenic variants of genes associated with pulmonary arterial hypertension (PAH): Insights from Trans-Omics for Precision Medicine (TOPMed) study participants

Vasile Foris

Poster

Abstract

Pulmonary vascular phenotype identified in patients with GDF2 (BMP9) or BMP10 variants: An international multicentre study

Julien Grynblat

Poster

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Glycoprotein IIb/IIIa-ICAM-1 mediated platelet-endothelial adhesion aggravates pulmonary hypertension

Bai Qianwen

Poster

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Identification of integrin a5b1 inhibition as a potentially disease-modifying approach for the treatment of pulmonary arterial hypertension

Monica Montesinos

Poster

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Role of ATP Citrate Lyase (ACLY) in Vascular Remodeling

Yann Grobs

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Reduced SOX17 in HPAECs drives CXCL10/11 upregulation and CXCR3-dependant lymphocyte migration in vitro

Abdul Mahomed

Ifan Jenkin

Poster

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Aurora kinase B: A New Therapeutic Target in PAH

Sarah-eve Lemay

Poster

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Reverse remodeling and anti-proliferative effects of seralutinib in PAH precision-cut lung slices and pulmonary artery smooth muscle cells

Soni Savai Pullamsetti

Poster

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Utilising self-similarity to model the morphometry of the pulmonary arteries

Atefeh Rahimi

Poster

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Late Breaking Abstract - A risk score including parenchymal lung disease improves risk stratification in Group 3 Pulmonary Hypertension

Krit Dwivedi

Poster

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CDN Connection Issue

The ERS Congress 2024, Vienna

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