Targeting lung fibroblast senescence to restore ECM regulation in COPD - Milan 2023

Translational approaches in fibrotic lung diseases: from bench to bedside

Chair(s): Carlos Esteban Machahua Huamani, Isis Enlil Fernandez

Session type: Poster session

Targeting lung fibroblast senescence to restore ECM regulation in COPD

Roy R. Woldhuis

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Effects of macrophage transplantation in bleomycin-induced pulmonary fibrosis in mice

Eiko Suzuki

Poster

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Loss of cofilin 1 in the airway epithelium of COPD causes mitochondrial dysfunction

Venkataramana Sidhaye

Poster

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Late Breaking Abstract - Calcaratarin D, a labdane diterpenoid, attenuates TGF-?1-induced airway epithelial-mesenchymal transition and lung fibroblast activation

Wupeng Liao

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Late Breaking Abstract - GTX-011 alleviates inflammatory, cardiovascular and pulmonary disfunction in a rat model of bleomycin-induced pulmonary fibrosis.

Eugenia Ruiz-canovas

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Role of apoptosis signal-regulating kinase-1 (ASK1) in the development of pulmonary fibrosis

Martina Korfei

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Lower proportion of collagen type XIV in lung tissue of patients with Idiopathic Pulmonary Fibrosis (IPF)

Mehmet Nizamoglu

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Extracellular vesicles regulate fibroblasts to myofibroblasts transition in chronic lung diseases

Xu Bai

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Sigma-1 receptor agonist mitigates bleomycin-induced pulmonary fibrosis in mice

Adam Hosszu

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Elastase inhibitory activity (EIA) in Chronic Obstructive Pulmonary Disease (COPD) and Alpha-1 Antitrypsin Deficiency (AATD)

Georgina Farago

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Succinate aggravates pulmonary fibrosis through the succinate/SUCNR1 axis.

Rishi Rajesh

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Resolvin E3 inhibits phosphorylation of p38 MAPK signaling pathway leading to the reduction of TGF-?1 production on macrophage

Masakiyo Yatomi

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Targeting lung fibroblast senescence to restore ECM regulation in COPD

Roy R. Woldhuis

Poster

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Dexamethasone restores TNF?-induced epithelial barrier dysfunction in primary rat alveolar epithelial cells

Naokata Kutsuzawa

Poster

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Real-life experience using nintedanib as a reference item in a preclinical rat model of bleomycin-induced fibrosis

Pan Filis

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The role of prostaglandin E2 (PGE2) on fibroblast - extracellular matrix (ECM) interaction in idiopathic pulmonary fibrosis (IPF): A pilot study

David Shitrit

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Effect of the HDACs inhibitor, Panobinostat, in a rat model of pulmonary fibrosis

Vanessa Pitozzi

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Interalveolar pores and association with (pre-)COPD stage and small airways

Stijn Verleden

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Late Breaking Abstract - Investigation of cKIT driven bone marrow toxicity and translation to human

Marie Larsson

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CDN Connection Issue

The ERS International Congress 2023, Milan

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