Abnormal phosphorylation of Per2 induces myofibroblast transformation and promotes the development of pulmonary fibrosis - Milan 2023

Basic mechanism and novel treatment targets in pulmonary fibrosis

Chair(s): ARGYRIS TZOUVELEKIS, Vanesa Vicens Zygmunt

Session type: Poster session

Abnormal phosphorylation of Per2 induces myofibroblast transformation and promotes the development of pulmonary fibrosis

Mei Chen

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A multicenter study of extracellular vesicles profile in bronchoalveolar lavage from patients affected by IPF, HP and sarcoidosis

Miriana D'alessandro

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Seoyeong Baek

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Hyeon Kyu Choi

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Abstract

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Sara Bozzini

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Abstract

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Wei Wang

Abstract

Intratracheal administration of a PROTAC with subnanomolar potency induces BRD4 degradation in the lung without systemic target engagement

Ulf Hedstrom

Poster

Abstract

Novel waveform analysis reveals persistent pathophysiological changes in rodent model of pulmonary fibrosis

Maria Volovaya

Poster

Abstract

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Mari Nogami-itoh

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Abstract

CycloZ improves pulmonary fibrosis in bleomycin-induced idiopathic pulmonary fibrosis model mice by modulating the pathogenic transcriptome.

Dohyun Lee

Poster

Abstract

A clinical-stage RNAi therapeutic candidate for IPF mediates durable MMP7 silencing in nonhuman primates and human lung tissue

Tingting Yuan

Poster

Abstract

Abnormal phosphorylation of Per2 induces myofibroblast transformation and promotes the development of pulmonary fibrosis

Mei Chen

Abstract

Use of invasive lung function assessment (DSI/Buxco) to quanity changes in lung function parameters in a rat bleomycin model of lung fibrosis.

Mary Mcelroy

Abstract

Impact of Bifidobacterium longum BB536 on nausea caused by pirfenidone in a mouse model of pellagra

Koji Kuronuma

Poster

Abstract

Bleomycin does not directly cause fibrosis in precision-cut lung slices, PCLS

Satoshi Kanazawa

Poster

Abstract

Preclinical evaluation of Ezetimibe for repurposing to pulmonary fibrosis.

Chanho Lee

Poster

Abstract

A novel senolytic drug, ARV-825, ameliorates experimental lung fibrosis

Seidai Sato

Poster

Abstract

Aging disturbed lysosomes to modulate efferocytosis-induced SPP1-expressing macrophage and inhibit pulmonary fibrosis reversal

Yue Zhang

Poster

Abstract

CDN Connection Issue

The ERS International Congress 2023, Milan

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