TP230 - PolyI:C and doxorubicin induce a senescent phenotype in basal cells, resulting in impaired lung organoids

Poster Session 2

Chair(s): Peter Openshaw, Hermelijn H. Smits, Philip Hansbro, Antoine-Emmanuel Saliba, Kaylee Worlock, Deepesh Dhakad, Dermot Linden

Session type: Thematic Poster

Michelle Brand

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TP201 Impact of GM-CSF on lung epithelial cell injury and repair in severe influenza virus pneumonia

Theresa Schafer

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TP234 Human induced pluripotent stem cell (hiPSC) derived lung organoids for disease modelling

Anna-lena Ament

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TP226 Interferon lambda activates the immunoproteasome thereby potentially regulating anti-viral immunity in the lung

Alexandra Sailer

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TP227 Eosinophil subtypes affect airway smooth muscle cells migration and ECM-related proliferation in asthma

Airidas Rimkunas

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TP228 Residual lung abnormalities following non-hospitalised COVID-19 infection

David Smith

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TP229 Respiratory gammaherpesvirus infection exacerbates experimental model of inflammatory bowel disease

Alexis Balthazar

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TP230 PolyI:C and doxorubicin induce a senescent phenotype in basal cells, resulting in impaired lung organoids

Michelle Brand

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TP232 Cytosolic DNA stress activates the immunoproteasome and primes adaptive T-cell immunity

Laylan Bramasole

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TP233 Primary human-derived airway organoid and immune cell co-cultures to facilitate viral infection and drug screening assays

Georgios Stroulios

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TP235 Histamine and IL-4 alter airway basal cell differentiation and mobility after injury

Emma Ruysseveldt

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TP224 Direct OM-85 airway administration: a new route to prevent viral infections and reduce associated inflammatory sequelae

Christian Pasquali

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TP237 Thioredoxin-1 and soluble interleukin-5 receptor subunit alpha as biomarkers of allergic and non-allergic asthma

Jolita Palacionyte

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TP238 Lack of IL-33 induction in transcriptional response of primary bronchial epithelial cells in asthma patients

Akshaya Keerthi Saikumar Jayalatha

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TP239 Clinical significance of macrophage-lymphocyte rosettes(MLRos) formation in patients with bronchial asthma(BA)

Tamar Saralidze

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TP240 Preventive intranasal flagellin protects against a multidrug resistant strain of P. aeruginosa by restoring the effect of gentamicin

Ana Raquel Conduto Dias Maia

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TP241 Effect of hybrid rehabilitation on exercise tolerance and peripheral muscle strength in patients with long COVID-19 syndrome

Angelos Vontetsianos

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TP242 Involvement of the CXCL12/CXCR4 axis in skeletal muscle wasting in a murine model of early Chronic Obstructive Pulmonary Disease (COPD)

Pauline Henrot

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TP243 Kinetics of immune subsets in COVID-19 patients treated with corticosteroids

Apostolos Pappas

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TP225 Single-cell transcriptomic analysis reveals an altered bronchial epithelial cell differentiation in asthma

Aurore Gay

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TP223 UPF1 is a novel factor in rhinovirus pathogenesis that is deficient in patients with severe asthma

Rocio Teresa Martinez-nunez

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TP202 Resolution of inflammation in long COVID

Sean Knight

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TP210 COVID-19 pneumonia hospitalizations in different phases of the pandemic in the United States: patient characteristics and clinical outcomes

Stijn Hollemeersch

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TP203 Pulmonary impaired COVID-19 patients show pro-fibrotic serum biomarkers after 4 months

Carlos Esteban Machahua Huamani

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TP204 Co-cultured, human alveolar organoids recapitulate epithelial-mesenchymal crosstalk in fibrotic lung disease

Carola Voss

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TP205 Cellular senescence in severe COPD bronchial epithelium impairs responses to human rhinovirus infection

Hong Guo-parke

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TP206 Cigarette smoke delays murine innate immune response against X31 influenza infection

Jelmer Vlasma

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TP207 Cigarette smoke induced transient and persistent proteome changes

Marie Zoller

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TP208 A circular RNA regulates ion conductance in cystic fibrosis bronchial epithelium

Chiara De Santi

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TP209 COVA: results of a double-blind, placebo-controlled phase 2/3 study to assess efficacy and safety of BIO101 in hospitalized COVID-19 patients

Suzana Lobo

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TP211 Tnfsf14-driven apoptosis of alveolar macrophages upon influenza infection enables the establishment of secondary pneumococcal pneumonia

Christina Malainou

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TP222 Viral pneumonia elicits a lung epithelial repair program in transdifferentiating alveolar macrophages characterized by Plet1

Learta Pervizaj-oruqaj

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TP212 Lung stromal cell dynamics are altered by infection experience and ongoing antigen presentation following influenza re-challenge

Julie Worrell

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TP213 First study results of the P4O2 long COVID cohort

Nadia Baalbaki

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TP214 Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment

Nincy Debeuf

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TP216 Pulmonary function 3-6 months following COVID-19: the P4O2 COVID-19 study

Merel E.b. Cornelissen

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TP217 Delineating the immune response of lung alveolar macrophages, CD4+ and CD8+ T-cells to viral PAMPs using live microscopy

Shaalan Yasmin

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TP218 Impact of the SARS-CoV-2 pandemic on benralizumab-treated patients with severe eosinophilic asthma

Nimrod Laszlo

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TP220 Defining the role of SARS-CoV-2 ?v?6 integrin binding in the pathogenesis of COVID-19 induced lung damage

Federica Monduzzi

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TP221 Association between cytomegalovirus seropositivity and severity of pulmonary fibrosis

Ana Serezani

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TP244 Outcome in total lung capacity associated with oropharyngeal microbiota relative to COVID-19-related ARDS status

Sabine Stadler

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Lung Science Conference 2023

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