Lead optimization and mode-of-action elucidation for novel antifibrotics - Vienna 2024

Therapeutic interventions and nutrition in lung health and disease

Chair(s): Manuela Funke-Chambour, Mustafa Abdo

Session type: Poster session

Lead optimization and mode-of-action elucidation for novel antifibrotics

Kevin Merchant

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Effect of the novel senolytic drug, BCL-xL PROTAC, on small airway epithelial cells in COPD

Justine Devulder

Poster

Abstract

TGF? drives fibrotic remodeling via modulation of homeostatic and pathological fibroblast populations in a murine model of pulmonary fibrosis

Michael Beers

Poster

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Late Breaking Abstract - KLF2 inhibits mechanical ventilation-induced lung injury by restoring the mitochondrial function of AEC2

Juntang Yang

Poster

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LSC - 2024 - Sigma-1 receptor agonist mitigates bleomycin-induced pulmonary fibrosis in mice

Adam Hosszu

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Virlaza® Demonstrates Profound Anti-inflammatory Effects Against Viral and Bacterial Infections: From Laboratory Research to Clinical Application

Rodolfo P Vieira

Poster

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Repetitive human UC-MSC administration limits the progression of pulmonary fibrosis induced by repetitive bleomycin instillation

Joan Truyols Vives

Poster

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Treatment with angiotensin-(1-7) shows a prolonged effect in an experimental model of chronic asthma with the maintenance of the allergen challenge

Igor Antonio Carvalho-ribeiro

Poster

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Effect of the putative senotherapy, Fisetin on small airway epithelial cells in COPD

Justine Devulder

Poster

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MicroRNA-135a-5p suppresses the CaSR-NLRP3 inflammasome axis and protects against sepsis-induced acute lung injury

Salman Khan

Poster

Abstract

Lead optimization and mode-of-action elucidation for novel antifibrotics

Kevin Merchant

Poster

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Whey Protein Supplementation Improves Lung Function, Functional Capacity and Respiratory and Peripheral Muscle Strength in Healthy Older Adults

Rodolfo P Vieira

Poster

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Investigation of heme-induced lung injury in human precision cut lung slices using a proteomics approach.

Namrata Kewalramani

Poster

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Jinshui Huanxian Formula Combined with Acupuncture inhibits Epithelial Mesenchymal Transition in Pulmonary Fibrosis Rats via TGF-?1/Smad Pathway

Chen Wang

Poster

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Inhibition of the de-ubiquitinse USP30 in human fibroblasts from IPF patients suppresses the fibrotic response

Ahmed Fahim

Poster

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High insulin inhibits ferroptosis and alleviates acute lung injury via LNC473-HIF1?-GPX4/FSP1 axis in obese mice

Shibo Guan

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A micropeptide MSTRG.1695.1-aa alleviates inflammatory-fibrosis pathological injury of lung tissue in COPD mice by suppressing EMT via targeting p38-MAPK

Xue Tian

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Antifibrotic property of pemafibrate during bleomycin-induced lung fibrosis

Sachi Matsubayashi

Poster

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Late Breaking Abstract - Epithelial CLEC2 protects against acute lung injury

Tian Jiang

Poster

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CDN Connection Issue

The ERS Congress 2024, Vienna

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