Seralutinib targets fibrotic pathways in IPF: Evidence from single-cell transcriptomics - Amsterdam 2025

From omics to targets: emerging insights into chronic pulmonary disease mechanisms

Chair(s): Arnaud Mailleux, Olivier Burgy

Session type: Oral presentation

Seralutinib targets fibrotic pathways in IPF: Evidence from single-cell transcriptomics

Rui Benfeitas

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Late Breaking Abstract - Reversing cleared lung samples for multi-dimensional analysis in therapeutic discovery

Leonor Simoes

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Poster

Abstract

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Lung function epigenetic markers across the lifespan

Sandra Casas Recasens

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Poster

Abstract

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Bi-allelic LAMP3 variants in childhood interstitial lung disease: a new surfactant-related disease. A CRC chILDEU study

Camille Louvrier

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Poster

Abstract

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Single-cell analysis of cryobiopsy samples from patients with early IPF reveals loss of alveolar epithelial cells, and emergence of aberrant basaloid cells

Aurélien Justet

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Abstract

Slides

Single-cell RNA sequencing of small airways of young persons who use e-cigarettes

Dina Yehia

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Poster

Abstract

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Genetic, spatial transcriptomic and functional links between IL-11 and pulmonary fibrosis (PF)

Marc Kaestle

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Poster

Abstract

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Proteomic Insights into Platelet Dysregulation and Pathogenic Mechanisms of Chronic Thromboembolic Pulmonary Hypertension

Lu Sun

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Poster

Abstract

Slides

Ikzf2 is identified as an eosinophil-basophil-mast cell (EBM) lineage marker and upregulated in asthma

Haoyu Tang

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Poster

Abstract

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Seralutinib targets fibrotic pathways in IPF: Evidence from single-cell transcriptomics

Rui Benfeitas

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Poster

Abstract

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Discussion and Q&A

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CDN Connection Issue

The ERS Congress 2025, Amsterdam

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