Integrated spatial and single-cell transcriptomics reveal PAK kinase as a therapeutic target in fibroblastic foci and dense fibrosis of IPF - Amsterdam 2025

Top scoring: bench to bedside in pulmonary fibrosis

Chair(s): GEORGE MARGARITOPOULOS, David Smith

Session type: Oral presentation

Integrated spatial and single-cell transcriptomics reveal PAK kinase as a therapeutic target in fibroblastic foci and dense fibrosis of IPF

Yuta Hirano

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Late Breaking Abstract - Autoantibody reduction treatment for acute exacerbations of idiopathic pulmonary fibrosis.

Steven Duncan

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Integrated spatial and single-cell transcriptomics reveal PAK kinase as a therapeutic target in fibroblastic foci and dense fibrosis of IPF

Yuta Hirano

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The PPFE atlas reveals distinct profibrotic and elastotic mesenchymal cellular archetypes in pleuroparenchymal fibroelastosis

Jannik Ruwisch

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The transcriptome of CD14+CD163-HLA-DRlow monocytes predicts mortality in Idiopathic Pulmonary Fibrosis

Theodoros Karampitsakos

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The early-stage lung immune infiltrate in patients with Idiopathic Pulmonary Fibrosis differentiate stable and progressive disease

Tamara Cruz Santa Cruz

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GM-CSF-engineered cell vaccine based on myofibroblast for the treatment of pulmonary fibrosis

Minyang Fu

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Intranasal MAF peptide vaccine for idiopathic pulmonary fibrosis therapy

Jiayu Wang

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Vaccination targeting ephrin-B2 ameliorates established pulmonary fibrosis

Jian Liu

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Plasma proteomic analysis in patients with idiopathic pulmonary fibrosis (IPF) from a phase 2 trial of admilparant

Toby M Maher

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Discussion and Q&A

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CDN Connection Issue

The ERS Congress 2025, Amsterdam

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