Osteoglycin fragment suppresses fibroblast activation and promotes lung tissue repair - Amsterdam 2025

Emerging mechanisms in interstitial lung disease

Chair(s): Theodore Kapellos, Madeleine Rossanese

Session type: Poster session

Osteoglycin fragment suppresses fibroblast activation and promotes lung tissue repair

Luke Van Der Koog

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Macrophage Plasticity in Pulmonary Fibrosis Pathogenesis and Resolution

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Epithelial-PCSK6 induces proliferation and decreases collagen deposition of fibroblasts through MMP activation

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Antifibrotics target discrete pathogen-associated inflammatory responses in lung cells

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Characterisation of Src-family kinase inhibitors in lung fibroblasts shows distinct signalling complexes required for matrix synthesis and differentiation

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AI-assisted automated Ashcroft scoring of lung fibrosis in spirometry-confirmed and bleomycin-induced mouse model of idiopathic pulmonary fibrosis

Linn Salto Mamsen

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Lung cellular senescence in a mouse model of idiopathic pulmonary fibrosis induced by repetitive bleomycin installations

Stine Jansen

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Osteoglycin fragment suppresses fibroblast activation and promotes lung tissue repair

Luke Van Der Koog

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Abstract

An antisense oligonucleotide targeting HSPB5 as an innovating therapeutic approach in pulmonary fibrosis

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CDN Connection Issue

The ERS Congress 2025, Amsterdam

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