Geographic variation in outcomes in RCTs of biologic therapies in patients with asthma or COPD: A systematic literature review - Amsterdam 2025

Biologics for asthma and allergic rhinitis: novel trial data

Chair(s): Alberto Papi, Ran Wang

Session type: Poster session

Geographic variation in outcomes in RCTs of biologic therapies in patients with asthma or COPD: A systematic literature review

David J. Jackson

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A Multinational Phase 2, Randomized, Double-Blinded, Placebo-Controlled Study to Evaluate the Effect of Linvemastat (MMP12 inhibitor) in Patients with Uncontrolled Asthma on Inhaled Corticosteroids (ICS) with Long-Acting Beta Agonist (LABA) as SOC

Bassem Elmankabadi

Poster

Abstract

Rapid and sustained FEV1 improvements with rademikibart in type 2 asthma: Impact of eosinophils and FENO

Raul Collazo

Poster

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Clinical remission in patients with asthma treated with twice-yearly depemokimab in the Phase III SWIFT-1/2 studies

Michael E. Wechsler

Poster

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Twice-yearly depemokimab demonstrates sustained pharmacokinetics and pharmacodynamics across Phase I and III trials

Stein Schalkwijk

Poster

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Geographic variation in outcomes in RCTs of biologic therapies in patients with asthma or COPD: A systematic literature review

David J. Jackson

Poster

Abstract

Twice-yearly depemokimab reduces exacerbations versus placebo in patients with asthma across age of onset/duration subgroups: Phase III SWIFT-1/2 studies

David J. Jackson

Poster

Abstract

Twice-yearly depemokimab demonstrates efficacy in patients with asthma across baseline medium- and high-dose ICS subgroups: Phase III SWIFT-1/2 studies

Ian D. Pavord

Poster

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Dose Optimization and Exposure-Response Analyses to Support the Dose Selection of TQC2731, a Novel Anti-TSLP Monoclonal Antibody, in Patients with Severe Asthma

Li Mei

Poster

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A Phase 1 randomized, double-blind study of safety, tolerability and pharmacokinetics of Solrikitug in healthy participants

Bojan Lalovic

Poster

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Rademikibart in moderate-to-severe asthma: Impact of eosinophils and regional differences on response

Raul Collazo

Poster

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Bronchoscopy measurements of tezepelumab pharmacokinetics and TSLP in asthmatic patients

Jacob Leander

Poster

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Predicting long-term remission with benralizumab in severe eosinophilic asthma (SEA): Post-hoc analysis of SIROCCO, CALIMA, BORA

David Price

Poster

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Relationship between early lung function improvement with dupilumab and long-term clinical improvement in chronic obstructive pulmonary disease

Frits M.e. Franssen

Poster

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Evaluation of ACQ-5 components from the rilzabrutinib phase 2 asthma study

Jorge Fernando Maspero

Poster

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First-in-human study of 9MW1911 (an anti-ST2 monoclonal antibody) in healthy volunteers

Danfeng Yin

Poster

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A study to investigate the safety, tolerability and pharmacokinetics of londamocitinib, an inhaled Janus kinase 1 inhibitor, in healthy Japanese and Chinese participants (NCT06519968)

Mohd Nubli Mustapa

Poster

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OCS reduction with tezepelumab in OCS-dependent patients with severe allergic, eosinophilic asthma in WAYFINDER

Guy Brusselle

Poster

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Absorption, distribution, metabolism, and elimination (ADME) study strengthens clinical pharmacology package of londamocitinib

Julia Lund

Poster

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APG808, an anti-IL-4R? monoclonal antibody, demonstrates safety, extended half-life, and sustained inhibition of type 2 inflammatory biomarkers

Amol Kamboj

Poster

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Twice-yearly depemokimab is well-tolerated in randomised, double-blind, placebo-controlled Phase III SWIFT and ANCHOR studies

Marjolein Cornet

Poster

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CDN Connection Issue

The ERS Congress 2025, Amsterdam

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