AmB exacerbates viral entry via GCase-mediated ceramide-dependent endosomal remodeling - Amsterdam 2025

Molecular and immunological pathways in respiratory infection and host defence

Chair(s): Aran Singanayagam, Karl J. Staples

Session type: Poster session

AmB exacerbates viral entry via GCase-mediated ceramide-dependent endosomal remodeling

Di He

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Etiology of severe community-acquired pneumonia (CAP), associated with non-alcoholic fatty liver disease (NAFLD)

Roman Razumnyi

Poster

Abstract

Holistic evaluation of the urbane exposome on wheezing and chest infections: An outcome-wide approach

Robin Mzati Sinsamala

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Abstract

AmB exacerbates viral entry via GCase-mediated ceramide-dependent endosomal remodeling

Di He

Poster

Abstract

AXL Drives Respiratory Viral Entry via GAS6-Dependent Endocytic Pathways: A Broad-Spectrum Therapeutic Target for Influenza and Beyond

Wenting Zuo

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Abstract

Dynamic role of virulence and antimicrobial resistance on mortality of Klebsiella spp. infections

Yunfei Tang

Abstract

Antiviral siRNA multiplex treatment reduces HPIV3 infection and modulates inflammation in human precision-cut lung slices.

Franziska Dahlmann

Poster

Abstract

Multi-omic analysis of pleural fluid reveals neutrophil heterogeneity in pleural infection

Yinzhou Feng

Abstract

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Alberto Papi

Poster

Abstract

Lack of S100A8 impairs lung protective immunity against Streptococcus pneumoniae in mice

Lena Ostermann

Abstract

Single-cell RNA sequencing reveals macrophage phenotypical and functional regulation by baseline MCMV infections in mice with bacterial pneumonia

Yan Hu

Poster

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Longitudinal measurements of cytokines and the probability of survival in septic respiratory tract infections

Adrian Ceccato

Poster

Abstract

Safety tolerability and proof of pharmacology of a dry powder formulation of the antiviral host defense enhancer INNA-051 in healthy adults aged 18-80

Christophe Demaison

Poster

Abstract

Neutrophil elastase and NETs contribute to disease exacerbation in pleural infection

Julia Chu

Poster

Abstract

Erdosteines active metabolite MET-1 enhances antibiotic activity against S.aureus and P.aeruginosa in vitro

Bailey Ramsden

Poster

Abstract

Role of antiviral retinoic acid-inducible gene I (RIG-I) signalling in H1N1 influenza infection on human primary nasal epithelium

Hugo Ombredane

Poster

Abstract

Effects of tyre and road wear particle (TRWP) on toxicity and respiratory virus infection on iPSC-derived human bronchial epithelium

Hugo Ombredane

Poster

Abstract

Pulmonary glycosaminoglycans and fucosylation regulate lung barrier function and defense against S. pneumoniae

Cengiz Goekeri

Poster

Abstract

How Lung Tissue Damage Improves by Moringa oleifera Leaves Extract in Rat Model Pneumonia

Jatu Aphridasari

Poster

Abstract

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The ERS Congress 2025, Amsterdam

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