Severe asthma with concomitant elevation of blood eosinophils and FeNO is associated with mast cell recruitment and activation - Amsterdam 2025

Mechanistic insights and therapeutic potential in asthma

Chair(s): Sejal Saglani, Pavol Pobeha

Session type: Poster session

Severe asthma with concomitant elevation of blood eosinophils and FeNO is associated with mast cell recruitment and activation

Freja Lajer

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Mechanisms of exosome Mir-126-5p regulation of asthma through the vascular endothelial-macrophage axis

Lanlan Zhang

Poster

Abstract

Role of Transglutaminase 2 in mucus plugging in asthma

Severine Letuve

Poster

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Late Breaking Abstract - CosMx subcellular spatial molecular imaging of bronchial biopsies from patients with severe eosinophilic asthma treated with mepolizumab. Preliminary results of the MESILICO study.

Kalliopi Domvri

Poster

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Late Breaking Abstract - Long-term effect of Mepolizumab on airway remodeling in patients with late-onset severe eosinophilic asthma with obstructive pattern: a 3-Year Follow-Up of the MESILICO study.

Kalliopi Domvri

Poster

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Bronchial smooth muscle extracellular vesicles interfere with bronchial epithelium metabolism and function in asthma

Elisa Celle

Poster

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Unraveling the role of serine/arginine-rich proteins in growth factor-induced GR? expression in asthmatic airway smooth muscle

Patricia Ramos-ramírez

Poster

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Reduced PCYT2 Expression Leads to Phospholipid Metabolism Abnormalities and Inflammatory Pathway Activation in Bronchial Epithelial Cells of Asthma Patients

Zemin Li

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Eosinophil subpopulations in different asthma endotypes and their correlation with disease severity

Matteo Accinno

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Bone morphogenetic protein receptor type 1B (BMPR1B) is associated with TSLP+ epithelial cells in T2-low SA

Kuan-yuan Chen

Poster

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Targeting estrogen receptors reduces platelet-leukocyte complexes and cell recruitment in lung inflammation

Alembert Lino Alvarado

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Unravelling survival and reactivation of pathogenic CD4 type-2 tissue-resident memory T cells in allergic asthma

Jannes Gavel

Poster

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Evaluation of granulocyte-derived microparticles between the airway and the blood

Jose Luis López-campos

Poster

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Farm dust modifies rhinovirus-induced antiviral and inflammatory responses in airway epithelial cell cultures

Jasmijn A. Schrumpf

Poster

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Severe asthma with concomitant elevation of blood eosinophils and FeNO is associated with mast cell recruitment and activation

Freja Lajer

Poster

Abstract

CD146 in bronchial epithelium: a contributor to epithelial dysfunction in severe asthma?

Florian Lepretre

Poster

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Mucosal CD8+ T cells correlate with measures of airflow limitation in adults born preterm

Mervi Kreus

Poster

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Novel guardians of respiratory mucosa: Microfold cell expansion upon chronic antigen challenge

Tsung-yu Pai

Poster

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Local immunity assessment at seven anatomical sites in the upper and lower airways: High immune cell recovery for detailed cell phenotyping

Renan M. Mauch

Poster

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Bronchial epithelial cells in asthma: Do they produce energy the right way?

Pierre-alexandre Gagnon

Poster

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Late Breaking Abstract - Obesity is associated with altered epithelial lipid storage and impaired mucociliary clearance of the human airways

Ayse Tugce Sahin

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The ERS Congress 2025, Amsterdam

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