Neutrophil elastase activity following cathepsin C (CatC, or DPP1) inhibition with BI 1291583 in people with bronchiectasis - Amsterdam 2025

Bronchiectasis: immunology, biomarkers, molecular profiles and targeted therapy

Chair(s): Eva Polverino, Merete Bridget Long

Session type: Poster session

Neutrophil elastase activity following cathepsin C (CatC, or DPP1) inhibition with BI 1291583 in people with bronchiectasis

James D. Chalmers

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Rebecca C Hull

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Abstract

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Rachel Galloway

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Merete Bridget Long

Abstract

Stiff circulating neutrophils and enhanced thrombogenic potential in bronchiectasis increases cardiovascular risk

Rebecca Evans

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Abstract

Factors related to the epigenetic profile in bronchiectasis

Lídia Perea

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Abstract

CC16: a biomarker of disease severity and Pseudomonas infection in Bronchiectasis

Pau Marrades Segura

Poster

Abstract

Neutrophil elastase activity following cathepsin C (CatC, or DPP1) inhibition with BI 1291583 in people with bronchiectasis

James D. Chalmers

Poster

Abstract

Association between neutrophil elastase activity in bronchial lavage fluid and the one-year follow-up exacerbation in bronchiectasis patients

Ho Lam Nguyen

Poster

Abstract

Subgroup analysis: AIRLEAF® Phase II study of a cathepsin C (CatC, or DPP1) inhibitor, BI 1291583, in adults with noncystic fibrosis bronchiectasis

James D. Chalmers

Poster

Abstract

Pooled data from Phase II studies (AIRLEAF®, CLAIRLEAF®) of the cathepsin C (CatC, or DPP1) inhibitor BI 1291583 in bronchiectasis

Michal Shteinberg

Poster

Abstract

Efficacy and safety of brensocatib in patients with non-cystic fibrosis bronchiectasis and Pseudomonas aeruginosa infection: Analysis of the ASPEN trial

Stefano Aliberti

Poster

Abstract

Effectiveness of mucoactives compared to standard care in adult bronchiectasis: A systematic review

Benjamin Mccullough

Poster

Abstract

Efficacy and safety of brensocatib in Japanese patients with non-cystic fibrosis bronchiectasis: Analysis of the ASPEN trial

Kozo Morimoto

Poster

Abstract

Expression of activation markers of circulating neutrophils and eosinophils in stable bronchiectasis

Andreas M. Matthaiou

Poster

Abstract

CDN Connection Issue

The ERS Congress 2025, Amsterdam

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