Repositioning a drug for hyperlipidemia as a potential senotherapeutic for aging-related respiratory diseases - Amsterdam 2025

Translational science in interstitial lung disease 2

Chair(s): Anne-Marie Russell, Maria Hollmén

Session type: Poster session

Repositioning a drug for hyperlipidemia as a potential senotherapeutic for aging-related respiratory diseases

Sachi Matsubayashi-Hosokawa

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UL ameliorates lung inflammation and pulmonary fibrosis by regulating the TGF-?/T?Rs signaling and autophagy

Wei-chung Chiou

Poster

Abstract

Inhibition of ogg1 a novel strategy for treating pulmonary fibrosis OXC-201 reduces inflammation and fibrosis, leading to improved lung function in mice

Sandra Ekstedt

Poster

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B Cell Dysregulation in Acute Exacerbation of Idiopathic Pulmonary Fibrosis

Dong-woo Han

Poster

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LPCAT1 as a Therapeutic Target for AT2 Regeneration in IPF

Anas Rabata

Poster

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AT2R agonists buloxibutid (Compound 21) and NAc inhibit fibrogenesis in human precision cut lung slices ex vivo

Olivia Young

Poster

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Characterization of Human Precision Cut Lung Slices as an ex vivo model for Idiopathic Pulmonary Fibrosis

Gessica Marchini

Poster

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Macrophage Fra-2 Promotes Pulmonary Inflammation and Fibrosis in a Mouse Model of Pulmonary Interstitial Fibrosis

Yun Liu

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The efficacy of Frankenia pulverulenta for the treatment of experimental lung fibrosis induced by Bleomycin in Wistar rats

Sana Bahri

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Advancing pulmonary fibrosis Treatment: Efficacy testing for new drug candidates on the ILD on-chip model

Ferdinand Ativon

Poster

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Tissue repair response in Non-Specific Interstitial Pneumonia compared to Idiopathic Pulmonary Fibrosis

Vijay Hadda

Poster

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Ganoderma microsporum immunomodulatory protein (GMI) ameliorates pulmonary fibrosis by regulating the PI3K/Akt/mTOR signaling

Tzu-lan Hsia

Poster

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A Vaccine Therapy for Idiopathic Pulmonary Fibrosis

Tianxia Lan

Abstract

PMEPA1 regulates the function of fibroblast through STAT3/p-STAT3/GLUT1 pathway to participate in the pathogenesis of IPF

Li Zhen

Abstract

Repositioning a drug for hyperlipidemia as a potential senotherapeutic for aging-related respiratory diseases

Sachi Matsubayashi-hosokawa

Poster

Abstract

The synergistic effects of pirfenidone and PPAR-alpha agonists in alleviating the profibrotic response in pulmonary fibrosis

Gani Oruqaj

Poster

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Evaluation of a PDGFR?-specific vector for targeted drug delivery in pulmonary fibrosis

Jan Willem Duitman

Poster

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Exploring the role of hypusine signaling in IPF

Sarah-eve Lemay

Poster

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The novel autotaxin inhibitor, 2-carba cyclic phosphatidic acid ameliorates bleomycin-induced lung fibrosis in mice.

Keiko Haji

Poster

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Cluster analysis of cytokines in bronchoalveolar lavage samples from patients with Interstitial Lung Diseases: an exploratory study

Joel Francesqui

Poster

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Late Breaking Abstract - PMG1015 demonstrates well-tolerated safety and favorable FVC changes after 12 weeks of treatment in IPF Patients

Toby M Maher

Poster

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CDN Connection Issue

The ERS Congress 2025, Amsterdam

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