HK2-Mediated Mitochondrial Glycolysis and Mitophagy Drive Hypoxic Alveolar Epithelial Injury in High-Altitude Pulmonary Edema - Amsterdam 2025

Innovations in acute lung injury mechanisms

Chair(s): Raquel Guillamat Prats, Reinoud Gosens

Session type: Poster session

HK2-Mediated Mitochondrial Glycolysis and Mitophagy Drive Hypoxic Alveolar Epithelial Injury in High-Altitude Pulmonary Edema

Bi Ran

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Functional heterogeneity of lysine lactylation of RNA splicing factors in ALI/ARDS

Abstract

Endothelial Sema6A promotes acute lung injury via PlexinA2-dependent vascular leakage

Renhui Huang

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Vascular endothelial growth factor isoform VEGF165b mediates the reduction of pulmonary vascular endothelial permeability in acute lung injury

Jia Deng

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ZBTB7B orchestrate the macrophage pyroptosis and facilitates the inflammatory injury of septic ARDS

Lunxian Tang

Poster

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Clustering endotypes of ARDS for the outcomes

Honglong Ji

Abstract

G-protein coupled receptor (GPR)55 deficiency protects lung damage by regulating neutrophil activation in an LPS-acute lung injury mouse model

Paula Goncalves Romeu

Poster

Abstract

HK2-Mediated Mitochondrial Glycolysis and Mitophagy Drive Hypoxic Alveolar Epithelial Injury in High-Altitude Pulmonary Edema

Bi Ran

Abstract

Acute Lung Injury Induced by Saturated Fatty Acid Deficiency

Tomoyuki Suzuki

Poster

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Phenotyping the heterogeneity of Acute Respiratory Distress Syndrome (ARDS) to test new pro-reparative treatments in human preclinical models

Tom Voisin

Poster

Abstract

An ATP6V0CHIF-1? positive feedback loop that aggravates acute lung injury

Abstract

An evaluation of Tie2 mRNA as a potential therapeutic for ventilator-induced lung injury

Shanshan Du

Poster

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Toxicological Impact of Benzo[a]pyrene (B[a]P) in Airway Epithelial Cell Models (NHBE and SAEC) Cultured Under the Air-Liquid Interface (ALI): A Potential Alternative to Animal Testing

Jeong-woong Park

Poster

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Dysbiosis caused by extreme temperature in mice lung

Zakari Abubakar

Poster

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ITIH4/MALAT1 pathway mitigates the pulmonary severity of acute respiratory distress syndrome

Yu-syuan Shih

Poster

Abstract

Frequent exacerbations and mucus-metabolic dysfunction characterizes an Asian subgroup with high-risk COPD

Kai Xian Thng

Poster

Abstract

Metabolic crosstalks: upregulated PARK7 due to histone lactylation rescues inhibited FADS1/2 of endothelial cells in acute lung injury

Jian Xu

Abstract

Artemin inhibits pulmonary inflammation of acute lung injury by inhibiting Saa3+ macrophages through HIF-1? induced glycolysis

Qiao Zhou

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Inflammation to Regeneration: The PARP1/miR-135a-5p Paradigm in Sepsis-induced Acute Lung Injury

Salman Khan

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CDN Connection Issue

The ERS Congress 2025, Amsterdam

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