YI03 – A novel IgA plasma cell niche in the human airways

YI04 – d Influenza infection of epithelial cells alters extracellular vesicle microRNA involved in viral replication and the immune response

YI05 – Resolving aging-related cellular phenotypes in pulmonary fibrosis by longitudinal single-cell transcriptomics

Tools for career development – Introduction

Effective teaching and mentoring: where to start?

How to collaborate successfully (industry vs academic perspective) – part 1

How to collaborate successfully (industry vs academic perspective) – part 2

Transferable skills: you are more than ‘just’ a scientist!

Setting the scientific playfield outside academia: a career in scientific editing

Panel discussion and networking event

Virus provided protection against allergic asthma

The cellular landscape of the airways in asthma

Cytokines targeted therapies in asthma versus COPD

Precision medicine: New biomarkers and targets beyond T2 inflammation

Role of lung microbiome in airway diseases

Conclusion by Reinoud Gosens, ERS Conferences and Seminars Director

Mentoring session: Exchanging & sharing tips on career plans / preparing the next career phase

Mentoring session: Reviewing training (how to be a good reviewer for grants/Papers etc)

Mentoring session: Tips on grant applications & management, including budget development and monitoring

Mentoring session: Preparing an outstanding oral presentation / how to prepare for an interview

Mentoring session: How to collaborate successfully on an international level (including more practical aspects such as material transfer agreements)

TP101 - Longitudinal impact of conjugated pneumococcal vaccine (PCV13) on cytokine profile in different asthma phenotypes

TP102 - A helminth glutamate dehydrogenase targets eicosanoid pathways to modulate type-2 immunity

TP103 - Characterization of neutrophilic responses in a pollutant-aggravated asthma mouse model

TP104 - Post-COVID: The multimodal path to the right treatment strategy

TP105 - Pulmonary In Vitro Perfusion (PIPE) Model to Study Cellular Crosstalk in Neonatal Pulmonary Vascular Disease

TP106 - Distinct metabolic reprogramming of airway epithelium in asthma in response to infection with rhinovirus

TP107 - Innate immunity plays an important role during NTHI and RV sequential infection.

TP108 - Antibiotic-induced microbial disruption drives metabolic rewiring in pulmonary macrophages and a dysregulated type 2 response in the lung

TP109 - Monocyte migratory signatures identify acute and convalescent COVID-19 patients, and are associated with long COVID-19 symptoms

TP110 - Phenotype and severity of asthma determines bronchial epithelial immune responses to a viral mimic

TP111 - Polymeric immunoglobulin receptor and immunoglobulin A system in an eosinophilic mouse model of chronic rhinosinusitis

TP113 - Specialized pro-resolving mediators’ biosynthesis by cystic fibrosis airway epithelial cells and their impact on mucociliary clearance

TP114 - Spatial ECM proteomics resolves instructive tissue niches in the distal human lung

TP115 - Insulin-like Growth Factor 1 Receptor facilitates NSCLC tumor growth acting in the tumor microenvironment

TP116 - Lineage tracing of cells expressing the mesenchymal profibrotic transcription factor Prrx1 in the normal and fibrotic lung

TP118 - Exploring IL13 effects on the remodeling of airway epithelial cell populations by single-cell RNA sequencing

TP119 - The chitinase-like protein Ym2 is an amplifier of innate type 2 responses

TP120 - Local airway expression of lnc-SERPINA12-1 in children with Cystic Fibrosis

TP121 - High-dimensional characterisation of the airway wall of paediatric patients with asthma and pre-school wheeze using Imaging Mass Cytometry

TP122 - Exploring the role of infection experienced lung stromal cells following re-challenge with influenza A virus

TP123 - Lung Cancer-Associated Fibroblasts in MHCII immunity: Understanding its Molecular Basis to Design Novel Immunotherapies

TP125 - Mapping the Immune Response Diversity after Murine Lung Transplantation

TP126 - Differential expression of PD-1/PD-L1 axis in mediastinal lymph nodes of experimental and human lung fibrosis

TP127 - Mitochondrial iron regulates AEC2 dysfunction, senescence and senescent associated secretory phenotype in response to bleomycin challenge

TP128 - Broncho-vascular mesenchymal stromal cells guided spatiotemporal establishment of antibody secreting cell pro-survival niches in the lung

TP129 - Pulmonary macrophage subsets associated with lung allograft dysfunction revealed by single-cell RNA sequencing

TP130 - Hyaluronan (HA) accumulation following SARS-CoV-2 infection and in non-resolvable COVID-19 fibrosis

TP131 - Biosynthesis and implementation of Thyroid Receptor beta (TRß) agonists (thyromimetics) for the treatment of pulmonary fibrosis

TP132 - Myeloid cells immunomodulate tissue niches and promotes idiopathic pulmonary fibrosis

TP134 - Circular RNA expression in cystic fibrosis bronchial epithelium

TP135 - Extracellular vesicles produced by airway epithelial cells from COPD patients contain miRNAs involved in cellular senescence

TP136 - Effects of blocking TSLP on ILC and T cell subpopulations in patients with asthma

TP137 - Construction of a 3D innervated bronchial epithelium from human induced pluripotent stem cells iPSC

TP138 - Alveolar macrophages from people with severe eosinophilic asthma show differential antiviral responses to human rhinovirus 16 and SARS-CoV-2.

TP139 - Regulation of MHC I expression in lung epithelial cells during inflammation

TP140 - Effect of eosinophilopoetins on proliferative properties of blood eosinophil subtypes in allergic asthma

TP141 - Kynurenine pathway as a modulator of inflammation in COPD and its exacerbations

TP143 - Inhibiting RIPK1 kinase activity is protective in experimental models of COPD

TP144 - Cigarette smoke modulates cellular responses of differentiated human bronchial epithelial cells to rhinovirus-A16 infection

TP202 - Targeting CXCR4 as a therapeutic strategy to improve outcomes in a mouse model of early chronic obstructive pulmonary disease (COPD)

TP203 - Reactivation of latent virus infection links air pollutants to chronic lung disease

TP204 - No differences in cytokine responses to moderate-intensity exercise in -10°C versus 10°C.

TP205 - Different Effects of Inhaled Corticosteroids on Infiltrating Mast Cells in Type 2 High and Type 2 Low Asthma

TP206 - Real time in vivo investigation of the innate immune response during ventilator-assisted nanoparticle inhalation

TP207 - Elevated ferritin is associated with systemic inflammation, inflammasome activation and mortality in Acute Respiratory Distress Syndrome (ARDS)

TP208 - Effects of probiotics in uncontrolled asthma

TP209 - Budesonide reduces the bronchial epithelial response to a viral mimic in T2high asthma, and boosts anti-microbial responses in T2low asthma

TP210 - Differential toxicity in an alveolar epithelial cell line of fine particulate matter from brakewear, roadwear, and diesel exhaust

TP211 - Inhaled continuous exposure to farmyard microbes suppress type 2 inflammation in a neonatal murine model of viral-induced wheeze and asthma

TP212 - Allergen exposure induces airway macrophage metabolic reprogramming

TP213 - Mast cell tryptase contribute to airway remodelling by inducing pro-survival and cell growth properties in lung epithelial cells

TP214 - The memory of airway epithelium damage in smokers and COPD patients

TP215 - Human lung microbiota drives differential innate immune response

TP216 - Expression of miR-185-5p, miR-146b-5p, miR-320b, miR-21-5p in Blood Eosinophil Subtypes and Plasma in Allergic Asthma Patients

TP217 - The role of IGF2BP3 in Type 2 signalling in bronchial epithelium: a novel player in severe asthma

TP218 - IL-13 modulates exosome production and miRNAs cargo in bronchial epithelial cells in severe asthma

TP219 - Function-specific IL17A and Dexamethasone interactions in primary human airway epithelial cells

TP220 - Impact of treatments targeting the GM-CSF pathway on the functions of human pulmonary macrophages

TP221 - Generation of apical-out airway organoids from human primary airway epithelial cells

TP223 - NTHi-IAV coinfection of macrophages alters infection outcomes and inflammatory responses

TP224 - Pseudomonas aeruginosa modulates mucosal immune response to rhinovirus infection in an in-vitro chronic infection model

TP225 - Chronic Bacterial Airways Infection in Severe Asthma

TP226 - The Cathelicidin LL-37 and microbial dysbiosis in COPD patients receiving inhaled corticosteroids

TP227 - Ex vivo modelling of human lung fibrogenesis and drug mode of action screens using single-cell RNA-seq in precision-cut lung slices

TP228 - G-protein coupled receptor 87 is a novel basal cell marker in distal IPF bronchioles

TP229 - Profiling systemic inflammation and neutrophil function in hospitalized patients with COVID19: results from PREDICT-COVID19

TP230 - The microbiota plays a critical role in the reactivity of lung immune components to innate ligands

TP231 - Modulation of antiviral responses to rhinovirus by the nonsense mediated decay pathway and implications in rhinovirus-induced exacerbations

TP232 - Extracellular vesicles and soluble factors secreted by lung fibroblasts support alveolar organoid formation

TP233 - Single cell transcriptomic dissection of virus induced immunopathology in interferon gamma receptor null mice

TP235 - Lung surfactant lipids reduce the alternative activation and proliferation of alveolar macrophages induced by IL-4

TP236 - Monocyte migration and COPD pathogenesis are epigenetically regulated by PRMT7

TP238 - Biomarker identification to assess effects of bone-marrow derived mesenchymal stromal cell-therapy in emphysema through immune profiling

TP239 - An ex vivo model of cellular senescence and inflammaging in precision-cut lung slices

TP240 - Support of human alveolar organoid growth by pulmonary endothelial cells: possible influence of cigarette smoke exposure

TP241 - Overzealous degradation of collagen fragment Pro-Gly-Pro by leukotriene A4 hydrolase (LTA4H) perpetuates fibrosis in IPF

TP242 - Mitochondrial DNA stress in lung parenchymal cells activates autoreactive CD8+ T cells - implications for pulmonary fibrosis

TP244 - Cigarette smoke and air pollution induce dysfunctional pulmonary microvascular endothelial repair

eP303 - The level of sIgA in nasal secretions and the incidence of complications in hospitalized patients with COVID-19 against an immunotropic drug

eP304 - CT scan imaging in acute infectious infiltrative lung disease before the covid-19 era

eP306 - The biological activity of interferons in post-COVID syndrome

eP307 - Mitochondrial alterations in T cells after invivo and invitro smoke exposure

eP308 - Serum Levels of Surfactant Protein-B (SP-B) as biomarker in IPF and ILD-SSc

eP309 - Single-cell analysis reveals airway epithelial cell-specific expression quantitative trait loci in asthma

eP310 - NK and T cell in patients with end-stage lung disorders waiting for lung transplantation in response to CMV infection.

eP311 - Protective effect of interferon type I on barrier function of human airway epithelium during rhinovirus infections in vitro

eP312 - Receptor-binding domain of SARS-CoV-2 facilitates internalization of 100 nm particles by neutrophils in conducting airway mucosa of mice.

eP315 - Eosinophilic exacerbations of chronic obstructive pulmonary disease (COPD) have elevated reactive oxygen species (ROS) release

eP316 - The metabolite succinate inhibits influenza virus replication through succinylation and nuclear retention of the viral nucleoprotein

eP317 - The glycosylated extracellular domain of MUC1 protects against SARS-CoV-2 infection at the respiratory surface

eP318 - Ionic Calcium in Blood as Early Marker of Severity in Patients with COVID-19

eP320 - Novel nasal virosome spray vaccine to protect against COVID-19

eP321 - Impact of cigarette smoke on caspases activation and gasdermin D cleavage in human macrophages

eP324 - Immune-Checkpoint expression on CD4, CD8 and NK cells in blood, BAL and lymph nodes of sarcoidosis

eP325 - Source-related composition and toxicological effects of shipping-associated particulate matter

eP326 - Diesel exposure favors lung cancer progression through induction of an inflammatory microenvironment

eP327 - Correlations between volumetric capnography and automated computed tomography quantitative analysis in patients with severe COPD

eP328 - Cigarette smoke extract promotes caspase-1 activation and IL-18 release in primary human bronchial epithelial cells

eP329 - The impact of virus infection on the development of Bronchopulmonary Dysplasia (BPD)

eP331 - Chronic unpredictable stress exacerbates allergic airway inflammation in mice.

eP332 - Cigarette smoke alters macrophage mitochondrial iron handling in COPD

eP333 - Physiomimetic culture of mesenchymal stromal cells affects macrophage activity in a paracrine manner.

eP334 - Features of submicroscopic structure of respiratory part of lungs in early stages of development of streptozotocin-induced diabetes mellitus

eP335 - Bronchiectasis in severe asthma is associated with eosinophilic airway inflammation and activation

eP336 - Using lung organoids to recapitulate HRas/NRas-double knockout alveolar maturation defects in mice

eP337 - A study to evaluate nasal mucosal IgA development in neonates using a non-invasive sampling method

eP338 - Decreased expression of S100A7/A8/A9 in severe asthmatics following bronchial thermoplasty

eP339 - Cooperation between fatty acid binding protein 5 and peroxisome proliferator-activated receptor gamma in regulating macrophage programming

eP340 - Understanding the cellular immune response in silicosis by exposing human lymphocytes to silica nanoparticles

eP341 - Synergistic action of apoptotic cells and surfactant protein A in boosting IL-4-dependent alternative activation of alveolar macrophages

eP342 - Transcriptional response to RSV in asthma primary bronchial epithelial cells: are the basal cells responsible for the reduced NF-kB response?

eP343 - Lung volume and density assessment over time in hospitalized COVID-19 patients

eP344 - Involvement of FGF21 in pulmonary fibrosis

eP345 - Prenatal exposure to ozone triggers development of lung diseases in offspring

eP346 - Exploring the anti-inflammatory effect of commensal lung microbiota members in a 3-D lung epithelial cell model

eP348 - Human mast cell differentiation optimization to study MRGPRX2-induced activation in vitro

eP349 - Human plasma-derived IgG protects against respiratory pathogens in an epithelial air-liquid interface model

eP350 - Diesel exhaust particles and TNF-alpha or LPS induce pro-inflammatory pathways, including TSLP expression, in bronchial epithelial cells

eP351 - End stage lung disease is characterized by a pro-inflammatory imbalance in the innate lymphoid cell compartment.

eP352 - Environmental Nanoparticle Exposure Triggers Herpesvirus Reactivation via MAPK Signaling Pathway

eP353 - Average Volume Assured Pressure Support Auto-titrating EPAP(AVAPS-AE) mode in Lung Cancer Patients with Respiratory Failure

eP354 - Nasal mucosal lining fluid (MLF) biomarkers for monitoring acute and chronic respiratory disease

eP355 - The effect of interferon-alpha-2b therapy on humoral immunity after COVID-19 infection

eP356 - Systematic review and meta-analysis of interstitial lung disease transcriptomics

eP357 - COVID-19 and smoking: Worse outcome from a surveillance analysis

eP358 - A novel non-invasive approach to quantify microRNA expression in nasal fluid from COPD patients using a microfluidic platform

eP359 - Relations between blood and tissue microbiome in sarcoidosis patients

eP360 - Novel alveolar macrophage-like model (ImmuPHAGE) as a platform for better mechanistic understanding for the fate of inhaled medicines.

eP362 - Community-based asthma assessment in young children: Adaptations for a multicentre longitudinal study in South Asia

eP363 - Interleukin-10 expressing regulatory B cells are decreased in blood of smokers and COPD patients

eP364 - Ferroptosis, induced by macrophages drives COPD pathogenesis

eP366 - Exosomes from EGFR-mutated adenocarcinoma induce a partial/hybrid EMT

eP368 - Multi-omics analysis reveals the NAD+ salvage pathway as defense mechanism against Streptococcus pneumoniae infection

eP369 - DNA-viruses modulates changes in B cells phenotype and auto-Abs in asthma

eP370 - Eosinophil-associated gene signature expression in U-BIOPRED severe asthma

eP372 - IL11 negatively impacts adult lung alveolar organoid formation

eP373 - Assessment of mucosal and systemic phagocytosis in Health Care Professionals (HCPs) in the post COVID-19 period

eP374 - Radiation modulates bronchial epithelial progenitor activity as assessed in organoid formation assays

eP376 - Epithelial and neutrophil responses to microbes in cystic fibrosis airways

eP377 - Characteristics of DNA repair capacity of peripheral blood lymphocytes from asthmatic patients with different phenotypes and severity

eP378 - Cytogenetic Alterations In Cells from Allergic and Non-Allergic Asthmatic Patients

eP379 - Phenotype and function of innate lymphoid cells in a murine model of impaired muco-ciliary clearance challenged with allergen

eP380 - Unravelling the role of miR-223 in the regulation of pollutant-aggravated allergic airway inflammation

eP381 - Respiratory and systemic effect of diet and exercise in obese mice

eP382 - The RNA binding proteins ZFP36L1 and ZFP36L2 exert genome-wide effects on airways epithelium and glucocorticoid responses

eP383 - Production and delivery of a recombinant modified superoxide dismutase protein to a rodent ARDS model by vibrating mesh nebulisation

eP384 - Validation of CXCL10 as a biomarker of respiratory tract infections detectable by lateral flow immunoassay

eP385 - High-sensitivity TSLP assay demonstrates a role of TSLP in eosinophilic and non-eosinophilic asthma.

eP387 - Favipiravir induced rhabdomyolysis in patient with severe COVID-19 pneumonia

eP388 - IL-10 induced by alum-adjuvanted acellular pertussis vaccine reduces its capacity to induce protective respiratory tissue-resident CD4 T cells

eP389 - Persistent COVID-19 symptoms and quality of life among the Dutch pediatric population

eP390 - Altered eicosanoid profile in association with nasal polyp severity in patients with chronic rhinosinusitis

eP391 - Airway hyperreactivity and type of acetylation as the predioctors of eosinophilic asthma in school-age children

eP392 - Influence of the long-term usage of inhaled corticosteroids on development of obesity and growth retardation in children with bronchial asthma

eP393 - A human ex vivo model to study the innate immune response to NTHi in the lung

eP395 - Allergic risk factors for severe asthma among preschool children: a descriptive-analytical study from rural Sri Lanka

eP396 - Comparing epithelial alarmin responses to different aeroallergens in bronchial epithelial cells from allergic asthma patients

eP397 - Development of novel alveolar and bronchial microphysiological systems for use in disease research and drug development.

eP398 - Tissue resident memory T cells are increased in the lungs of COPD patients

eP399 - Club cells are the primary source of pIgR in small airways

eP400 - Seroprevalence of SARS-CoV-2 immunoglobulins in a community-based population in Tizi-Ouzou, Algeria.

eP402 - Farm dust exposure decreases expression of IL-33 in primary bronchial epithelial cells in part by inhibiting STAT1 phosphorylation

eP404 - Lung tuberculosis characteristics in association with herpesvirus infection

eP405 - Haemophilus influenzae is associated with fibrotic phenotype of COVID-19 and idiopathic pulmonary fibrosis.

eP406 - LDH inhibition rescues pulmonary fibrosis features in human primary cellular models of IPF

eP407 - Inhalable textile microplastic fibers impair lung repair

eP408 - The impact of nasal colonization with Staphylococcus aureus and its enterotoxin B on allergic airway inflammation in patients and mouse models

eP409 - Profibrotic and proinflammatory pulmonary response to bleomycin in a Swiss nude mice model

eP410 - Course of lung inflammation and injury caused by nanoparticle inhalation depends on material specific cellular perturbation pattern

eP412 - Altered hyaluronan metabolism in response to IL1ß in the lung microenvironment is associated with defective repair

eP414 - The bronchodilatory and anti-inflammatory effect of TRPV4 ion channels blocker in experimentally-induced allergic asthma.

eP415 - Investigation of the interplay of pattern recognition receptors in IFN responses in bronchial epithelial cells from asthma patients

eP416 - The role of mucosal IgE and cytokine levels in reflecting the intensity of allergic symptoms

eP417 - Igf1r deficiency attenuates lung inflammation in a mice model of sub-chronic cigarette smoke exposure

eP418 - Association between serum IgG levels and time to first antibiotic prescription in COPD patients

eP419 - Partial apoptosis of epithelial cells in Idiopathic Pulmonary Fibrosis(IPF).

eP420 - Exosomal miR16, miR21, miR126, miR146a and miR215 as biomarkers for asthma severity

eP421 - IL1ß induces RANKL secretion in control but not COPD lung fibroblasts

eP422 - One drug to rule them all: Targeting host cell metabolic pathway to combat respiratory infections

eP423 - Mucosal immunology of the gut and lung in a cigarette smoke-induced murine model for COPD: the lung-gut axis

eP424 - Deep learning in pulmonary drug delivery

eP425 - Fibroblasts drive the differentiation of murine pneumocytes in air-liquid interface cultures

eP426 - Prevalence and associated risk factors of post covid-19 interstitial lung disease; An emerging challenge to pulmonologists

eP427 - Outpatient antibiotic therapy leads to endotoxemia markers elevation in acute SARS-CoV-2 lung damage

eP428 - Local and systemic responses to SARS-CoV-2 infection in children and adults