Chair(s): Ane Johannessen, Apostolos Bossios, Howraman Meteran
Session type: Symposium
Shyamali Dharmage
Session content
Lung function and asthma trajectories and extrapulmonary comorbidities
Shyamali Dharmage
Slides
Ana Mocumbi
Replay
Slides
Seif Shaheen
Replay
Slides
Leonardo Fabbri
Replay
Slides
Replay
Session aims
To provide an expert overview of the current state of knowledge concerning patterns of lung function and cardiovascular and other comorbidities; to highlight that evidence is stronger for restrictive than obstructive defects; to clarify that chronic obstructive pulmonary disease (COPD)-comorbidity links are largely explained by known risk factors, whereas the restrictive lung function-comorbidity link has not been fully explored or explained; to present evidence from low- and middle-income countries linking a low forced vital capacity (small lungs) to cardiometabolic comorbidities; to demonstrate that part of the association between a restrictive defect (lower forced vital capacity) and cardiovascular comorbidity is explained by shared developmental signalling pathways; to describe the clinical and healthcare implications of comorbidities associated with COPD and impaired lung function; to describe how artificial intelligence techniques have contributed to lung function trajectory modelling; to provide take-home messages; to provide a deeper understanding of respiratory comorbidities and their clinical implications.