Alteration of Th1/Th2 axis in post-covid-19 pulmonary fibrosis - Amsterdam 2025

Preclinical insights into rare diseases

Chair(s): Gimano Amatngalim, Killian Hurley

Session type: Poster session

Alteration of Th1/Th2 axis in post-covid-19 pulmonary fibrosis

Geetanjali Bade

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Baicalein Attenuates CD8? T Cell-Mediated Cytotoxicity Against Bronchial Epithelial Cells by Inhibiting Perforin and Granzyme B

Xinru Xiao

Abstract

A primary ciliary dyskinesia in vitro model using CRISPR-edited clonal primary epithelial cells

Elizabeth Haughey

Poster

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Late Breaking Abstract - scRNA-seq analysis reveals that the fibrotic lung milieu amplifies pro-fibrotic effects of pulmonary macrophage transplantation by inducing recipient macrophages to adopt fibrotic characteristics and interact with immune cells via fibrotic signaling

Jun Ikari

Poster

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Late Breaking Abstract - Targeting senescence to reduce inflammation in alpha-1 antitrypsin deficiency (AATD)

Lucy Kirwan

Poster

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Alpha-1 Antitrypsin deficiency intensifies experimental mucosecretory disease in a hybrid mouse model

Gary P. Anderson

Poster

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CFTR genotype affects miRNA expression profile in response to innate immunity triggers in airway epithelial cells.

Aleksandra Szczepankiewicz

Poster

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Alteration of Th1/Th2 axis in post-covid-19 pulmonary fibrosis

Geetanjali Bade

Poster

Abstract

NEUTROPHIL EXTRACELLULAR TRAPS MEASUREMENT IN BRONCHOALVEOLAR LAVAGE FLUID OF PATIENTS WITH INTERSTITIAL LUNG DISEASE: A POSSIBLE BIOMARKER IN FIBROSIS?

Bianca Peixoto

Poster

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Identification of novel markers of progression in Idiopathic Pulmonary Fibrosis (IPF) and Chronic Hypersensitivity Pneumonitis (CHP)

Megan Mckean

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Resolution of Inflammation is Impaired in the Sugen-Hypoxia Mouse Model of Pulmonary Arterial Hypertension

Chloe Landy

Poster

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Transcriptomic effects of Azithromycin on airway basal cells in CCDC39 primary ciliary dyskinesia

Zofia Varenyiova

Poster

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Responsiveness of ciliary movement to ATP in primary ciliary dyskinesia with a long deletion in DRC1

Miki Abo

Poster

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RNA editing to correct the Z-allele in models of alpha-1 antitrypsin deficiency allows for maintenance of acute phase response

Maria Strakosha

Poster

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Seralutinib demonstrates in vitro reduction of vascular inflammatory drivers underlying pulmonary hypertension

Zhaoqing Ding

Poster

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Double-stranded RNA-induced macrophage pyroptosis: molecular mechanisms and impact on fibroblast activation

Lara Di Leonardo

Poster

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Inflammatory pattern in upper airway epithelium of Cystic Fibrosis patients

Elena Pohl

Poster

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TGF-?/Smad signalling through Nrf2 activation which alters the fibrotic phenotype in experimental pulmonary fibrosis

Arindam Bhattacharyya

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Bone marrow Mesenchymal Stromal Cells stimulated with Pulsed Electromagnetic Fields for the treatment of pulmonary fibrosis

Sara Bozzini

Poster

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Late Breaking Abstract - SOAT1-Mediated Lipid Dysregulation Drives PHMG-Induced Pulmonary Fibrosis: Therapeutic Potential of Avasimibe

Yuchao Ding

Poster

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The ERS Congress 2025, Amsterdam

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