A novel perfused muscle-on-chip platform to study muscle impairments in COPD - Amsterdam 2025

Ex vivo modelling in lung research: new frontiers

Chair(s): Niki L. Reynaert, Antonella Dost

Session type: Poster session

A novel perfused muscle-on-chip platform to study muscle impairments in COPD

Sven Manse

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Cell type-specific origins of oxidative/nitrosative stress drive the development of distinct COPD phenotypes

Stefan Hadzic

Abstract

Protective effects of a KEAP1 inhibitor in preclinical lung models of oxidative stress and cell damage

Karolina Öst

Poster

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LSC - 2025 - Investigating the mechanisms through which lung MSCs regulate endothelial functionality in COPD using distal lung organoid models

Mark Bell

Abstract

3D Lung Organoids as a Novel Model for Studying Ischemia-Reperfusion Injury in Lung Transplantation

Rosaria Tinnirello

Poster

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Ex Vivo Deposition and Pharmacokinetics of Inhaled RNA Therapeutics: Insights from the Isolated Perfused Rat Lung

Dorothee Winterberg

Poster

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WISP1 modulates inflammation and Oxidative Stress in COPD: evidence from a Lung-on-chip model

Maria Elpida Christopoulou

Poster

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Interleukin-21 exacerbates acute lung injury by increasing pulmonary microvascular endothelial permeability

Qiao Luo

Poster

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Pulmonary vascular leak: In vitro modelling of the microvasculature under flow conditions

Aoife Blake

Poster

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Cold storage of human Precision-Cut Lung Slices preserves cellular composition and transcriptional responses and enables on-demand translational lung research

Maria Camila Melo Narvaez

Poster

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Dynamic Pulmonary Aciniform Organoids for fibrosis modeling via mechanical expansion assessment

Satoshi Ikeo

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Small airways, big questions: how small airway disease relates to emphysema in COPD explant lungs

Thibo Verheyen

Poster

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The DDR1-TLN1 axis contributes to collagen synthesis in a chronic in vitro model of lung fibrogenesis.

Annabel Kunzemann Martinez

Poster

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Label-free 4D-imaging of pathophysiological cell and tissue changes in precision-cut lung slices

Naomi Esmee Duits

Poster

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Contributions from alveolar cell extrusion to cell-state transitions in lung fibrosis

Isabel Uwagboe

Poster

Abstract

A novel perfused muscle-on-chip platform to study muscle impairments in COPD

Sven Manse

Poster

Abstract

Attenuation of ventilation-induced endoplasmic reticulum stress associated with lung injury through phosphoinositide 3-kinase-? in a murine endotoxemia model

Li-fu Li

Abstract

Secretome profile of human alveolar epithelial type 2 cells from healthy and COPD subjects cultured in decellularised human lung slices

Anna-karin Larsson-callerfelt

Poster

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Late Breaking Abstract - Single-cell RNA sequencing reveals modified basal and club cells subtypes and accelerated aging in transplant recipients in an ex vivo airway epithelium model

Louise Bondeelle

Poster

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CDN Connection Issue

The ERS Congress 2025, Amsterdam

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